| Title | Dr. | First Name | Pau | Last Name | Sang |
|
|
|---|---|---|---|---|---|---|---|
| Designation | Assistant Professor | ||||||
| Department | Department of Microbiology SDC | ||||||
| pbsang@microbio.du.ac.in | |||||||
| Webpage | |||||||
| Phone.no | 011-24157169 | ||||||
| Employement Info | |||||||
|---|---|---|---|---|---|---|---|
| Employee Type | Nature Of Employment | ||||||
| Teaching | Permanent | ||||||
| Educational Qualifications | |||||||
|---|---|---|---|---|---|---|---|
| Degree/Certification Name | Institution | Year of Completion | |||||
| Ph.D. - Ph.D in Biological Science | Indian Institute of Science | 2015 | |||||
| PG | Indian Institute of Science | 2009 | |||||
| UG | Delhi University | 2007 | |||||
| Qualifications | |||||||
|---|---|---|---|---|---|---|---|
| Examination Name | Conducting Body | Date of Passing | |||||
| NET | CSIR | 08-09-2009 | |||||
| Fellowship Details | |||||||
|---|---|---|---|---|---|---|---|
| Name Of Fellowship | Awarding Body | Fellowship Level | |||||
| JRF | CSIR | National | |||||
| SRF | CSIR | National | |||||
| Teaching Experience (Within Institution) | |||
|---|---|---|---|
| Designation | Duration | ||
| Assistant Professor | 25-02-2022 To 31-12-2022 (10 months, 6 days) | ||
| Administrative Experience (Outside Institution) | |||||
|---|---|---|---|---|---|
| Designation | Institute | Duration | |||
| Staff Scientist | Loyola University | 16-03-2020 To 31-01-2022 (1 years, 10 months, 15 days) | |||
| Postdoctoral Research Associate | University of Texas Health Science Center at Tyler (UTHSCT) | 03-03-2017 To 13-03-2020 (3 years, 10 days) | |||
| Postdoctoral Fellow | Institute of Human Genetics - CNRS -University of Montpellier | 01-06-2015 To 28-02-2017 (1 years, 8 months, 27 days) | |||
| Courses/Subjects Taught | ||||||
|---|---|---|---|---|---|---|
| Teaching Activity Type | Course Title | Semester | Total Assigned Classes | Number of Classes Taught | Duration | |
| Lecture | Bacteriology | 1 | 60 | 60 | 12-12-2022 To 23-03-2023 (3 months, 11 days) | |
| Research Supervision Overview | |||||||
|---|---|---|---|---|---|---|---|
| PhD Scholars Supervised | PhD Degrees Awarded | Theses Submitted | |||||
| M.Phil Scholars Supervised | M.Phil Degrees Awarded | M.Phil Theses Submitted | |||||
| 0 | 3 | 0 | |||||
| Research Publications | |||||||
|---|---|---|---|---|---|---|---|
| Title of Article | Type of Publication | Name of Journal | ISSN | Journal Volume | Year | Link to Article | DOI (Digital Object Identifier) |
| Human CST complex restricts excessive PrimPol repriming upon UV induced replication stress by suppressing p21 | Research Papers in Web of Science Listed Journals | Nucleic Acid Research | Feb, 2024 | 2024 | https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkae078/7606965 | https://doi.org/10.1093/nar/gkae078 | |
| A distinct physiological role of MutY in mutation prevention in mycobacteria | Research Papers in Peer Reviewed Journals | Microbiology | 156 | ||||
| Novel insertion and deletion mutants of RpoB that render Mycobacterium smegmatis RNA polymerase resistant to rifampicin-mediated inhibition of transcription | Research Papers in Peer Reviewed Journals | Microbiology | 156 | ||||
| Biochemical properties of MutT2 proteins from Mycobacterium tuberculosis and M. smegmatis and their contrasting antimutator roles in Escherichia coli | Research Papers in Peer Reviewed Journals | Journal of bacteriology | 195 | ||||
| Mycobacterium tuberculosis MutT1 (Rv2985) and ADPRase (Rv1700) proteins constitute a two-stage mechanism of 8-oxo-dGTP and 8-oxo-GTP detoxification and adenosine to cytidine mutation avoidance | Research Papers in Peer Reviewed Journals | Journal of Biological Chemistry | 288 | ||||
| Crystallization and preliminary X-ray characterization of MutT2, MSMEG\_5148 from Mycobacterium smegmatis | Research Papers in Peer Reviewed Journals | Acta Crystallographica Section F: Structural Biology Communications | 70 | ||||
| A unique uracil-DNA binding protein of the uracil DNA glycosylase superfamily | Research Papers in Peer Reviewed Journals | Nucleic acids research | 43 | ||||
| Structural insights into the specificity and catalytic mechanism of mycobacterial nucleotide pool sanitizing enzyme MutT2 | Research Papers in Peer Reviewed Journals | Journal of Structural Biology | 204 | ||||
| Covalent binding of uracil DNA glycosylase UdgX to abasic DNA upon uracil excision | Research Papers in Peer Reviewed Journals | Nature chemical biology | 15 | ||||
| Base excision repair pathways of bacteria: new promise for an old problem | Research Papers in Peer Reviewed Journals | Future medicinal chemistry | 12 | ||||
| A predictable conserved DNA base composition signature defines human core DNA replication origins | Research Papers in Peer Reviewed Journals | Nature communications | 11 | ||||
| Roles of OB-fold proteins in replication stress | Research Papers in Peer Reviewed Journals | Frontiers in Cell and Developmental Biology | 8 | ||||
| Actin R256 mono-methylation is a conserved post-translational modification involved in transcription | Research Papers in Peer Reviewed Journals | Cell reports | 32 | ||||
| CST in maintaining genome stability: Beyond telomeres | Research Papers in Peer Reviewed Journals | DNA repair | 102 | ||||
| Human CST complex protects stalled replication forks by directly blocking MRE11 degradation of nascent-strand DNA | Research Papers in Peer Reviewed Journals | The EMBO Journal | 40 | ||||
| Non-Journal Publications | |||||||
|---|---|---|---|---|---|---|---|
| Title of Publication | Type of Publication | Publisher | Role | ISBN | Year | Link to Publication | Level |
| DNA Replication Stress and Genome Instability in Breast Cancer | Chapters in Books | Wiley | Co-Author | 9783527351756 | https://onlinelibrary.wiley.com/doi/epdf/10.1002/9783527841165.ch2 | International | |
| Research Projects | ||||||
|---|---|---|---|---|---|---|
| Project Title | Project Type | Year Of Sanction | Outcome/Output | Duration | ||
| A system for epitope tagging of genes in Saccharomyces cerevisiae for protein-protein interaction studies and other applications | Minor | 2022 | The first objective to generate a plasmid system for epitope tagging is achieved. We were able to generate a set of 4 plasmids each for FLAG and HA tagging of proteins. Each FLAG and HA tagged with associated with HIS3, LEU2, URA3, KanMX marker for selection. So these plasmids can now be used to tagged any proteins of interest with either FLAG or HA and in the 4 different selectable marker. They can also be used for tagging multiple protein using the different marker. . However due to lack of time and resources the second objective to study the interaction of Cip1 and PCNA is still under progress. | 01-09-2022 To 31-03-2023 (6 months, 30 days) | ||
| Professional Development Programmes | |||||||
|---|---|---|---|---|---|---|---|
| Programme Title | Sponsoring Institution | Organizing Institution | Role | Type of Programme | |||
| Communication and Presentation skills in Classroom Teaching | University of Delhi | Delhi University Computer Center and ICT Academy. | Attendee | Faculty Development Programmes | |||
| Online one week Faculty Development Programme on Academic Administration | Self Sponsor | Ramanujan College | Attending | Faculty Development Programmes | |||
| One-month Faculty Induction Programme | Self Sponsor | Ramanujan College | Attending | Orientation Programme | |||