| Title | Dr. | First Name | Pau | Last Name | Sang |
|
|
|---|---|---|---|---|---|---|---|
| Designation | Assistant Professor | ||||||
| Department | Department of Microbiology SDC | ||||||
| pbsang@microbio.du.ac.in | |||||||
| Webpage | |||||||
| Phone.no | 011-24157169 | ||||||
| Employement Info | |||||||
|---|---|---|---|---|---|---|---|
| Employee Type | Nature Of Employment | ||||||
| Teaching | Permanent | ||||||
| Educational | |||||||
|---|---|---|---|---|---|---|---|
| Degree/Certification | Institution | Year | |||||
| Ph.D. - DNA repair proteins in Mycobacteria and their physiological importance | Indian Institute of Science | 2015 | |||||
| PG | Indian Institute of Science | 2009 | |||||
| UG | Delhi University | 2007 | |||||
| Qualifications | |||||||
|---|---|---|---|---|---|---|---|
| Examination Name | Conducted By | Date of Passing | |||||
| NET | CSIR | 2009-09-08 | |||||
| Fellowship | |||||||
|---|---|---|---|---|---|---|---|
| Fellowship Name | Fellowship Body | Level | |||||
| JRF | CSIR | National | |||||
| SRF | CSIR | National | |||||
| Teaching experience inside the Institution | |||||||
|---|---|---|---|---|---|---|---|
| Designation | Institution | Duration From | Duration To | ||||
| Assistant Professor | Delhi University | 2022-02-25 | 2022-12-31 | ||||
| Administrative experience outside the Institution | |||||||
|---|---|---|---|---|---|---|---|
| Designation | Institution Name | Duration from | Duration to | ||||
| Staff Scientist | Loyola University | 2020-03-16 | 2022-01-31 | ||||
| Postdoctoral Research Associate | University of Texas Health Science Center at Tyler (UTHSCT) | 2017-03-03 | 2020-03-13 | ||||
| Postdoctoral Fellow | Institute of Human Genetics - CNRS -University of Montpellier | 2015-06-01 | 2017-02-28 | ||||
| Subjects Taught | |||||||
|---|---|---|---|---|---|---|---|
| Activity Type | Course Title | From | To | Semester | Total Classes Assigned | Number of Classes Taught | |
| Lecture | Bacteriology | 2022-12-12 | 2023-03-23 | 1 | 60 | 60 | |
| Research Guidance | |||||||
|---|---|---|---|---|---|---|---|
| PhD scholars under Supervision | Awarded PhD | Submitted | |||||
| M.Phil Scholars – Under Supervision | Awarded Degree | Submitted | |||||
| 3 | |||||||
| Research Publications | |||||||
|---|---|---|---|---|---|---|---|
| Article Name | Publication Type | Journal Name | ISSN No | Volume | Year | URL | DOI |
| A distinct physiological role of MutY in mutation prevention in mycobacteria | Research Papers in Peer Reviewed Journals | Microbiology | 156 | 2010 | |||
| Novel insertion and deletion mutants of RpoB that render Mycobacterium smegmatis RNA polymerase resistant to rifampicin-mediated inhibition of transcription | Research Papers in Peer Reviewed Journals | Microbiology | 156 | 2010 | |||
| Biochemical properties of MutT2 proteins from Mycobacterium tuberculosis and M. smegmatis and their contrasting antimutator roles in Escherichia coli | Research Papers in Peer Reviewed Journals | Journal of bacteriology | 195 | 2013 | |||
| Mycobacterium tuberculosis MutT1 (Rv2985) and ADPRase (Rv1700) proteins constitute a two-stage mechanism of 8-oxo-dGTP and 8-oxo-GTP detoxification and adenosine to cytidine mutation avoidance | Research Papers in Peer Reviewed Journals | Journal of Biological Chemistry | 288 | 2013 | |||
| Crystallization and preliminary X-ray characterization of MutT2, MSMEG\_5148 from Mycobacterium smegmatis | Research Papers in Peer Reviewed Journals | Acta Crystallographica Section F: Structural Biology Communications | 70 | 2014 | |||
| A unique uracil-DNA binding protein of the uracil DNA glycosylase superfamily | Research Papers in Peer Reviewed Journals | Nucleic acids research | 43 | 2015 | |||
| Structural insights into the specificity and catalytic mechanism of mycobacterial nucleotide pool sanitizing enzyme MutT2 | Research Papers in Peer Reviewed Journals | Journal of Structural Biology | 204 | 2018 | |||
| Covalent binding of uracil DNA glycosylase UdgX to abasic DNA upon uracil excision | Research Papers in Peer Reviewed Journals | Nature chemical biology | 15 | 2019 | |||
| Base excision repair pathways of bacteria: new promise for an old problem | Research Papers in Peer Reviewed Journals | Future medicinal chemistry | 12 | 2020 | |||
| A predictable conserved DNA base composition signature defines human core DNA replication origins | Research Papers in Peer Reviewed Journals | Nature communications | 11 | 2020 | |||
| Roles of OB-fold proteins in replication stress | Research Papers in Peer Reviewed Journals | Frontiers in Cell and Developmental Biology | 8 | 2020 | |||
| Actin R256 mono-methylation is a conserved post-translational modification involved in transcription | Research Papers in Peer Reviewed Journals | Cell reports | 32 | 2020 | |||
| CST in maintaining genome stability: Beyond telomeres | Research Papers in Peer Reviewed Journals | DNA repair | 102 | 2021 | |||
| Human CST complex protects stalled replication forks by directly blocking MRE11 degradation of nascent-strand DNA | Research Papers in Peer Reviewed Journals | The EMBO Journal | 40 | 2021 | |||
| Human CST complex restricts excessive PrimPol repriming upon UV induced replication stress by suppressing p21 | Research Papers in Web of Science Listed Journals | Nucleic Acid Research | Feb, 2024 | https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkae078/7606965 | https://doi.org/10.1093/nar/gkae078 | ||
| Publications other than journal articles | |||||||
|---|---|---|---|---|---|---|---|
| Title of Publication | Type of Publication | Publisher | Role in Publication | ISBN Number | Year | URL | Level |
| DNA Replication Stress and Genome Instability in Breast Cancer | Chapters in Books | Wiley | Co-Author | 9783527351756 | 2023 | https://onlinelibrary.wiley.com/doi/epdf/10.1002/9783527841165.ch2 | International |
| Research Projects | |||||||
|---|---|---|---|---|---|---|---|
| Title of the Project | Project Type | Year Of Sanction | Output | Start Date | End Date | ||
| A system for epitope tagging of genes in Saccharomyces cerevisiae for protein-protein interaction studies and other applications | Minor | 2022 | The first objective to generate a plasmid system for epitope tagging is achieved. We were able to generate a set of 4 plasmids each for FLAG and HA tagging of proteins. Each FLAG and HA tagged with associated with HIS3, LEU2, URA3, KanMX marker for selection. So these plasmids can now be used to tagged any proteins of interest with either FLAG or HA and in the 4 different selectable marker. They can also be used for tagging multiple protein using the different marker. . However due to lack of time and resources the second objective to study the interaction of Cip1 and PCNA is still under progress. | 2022-09-01 | 2023-03-31 | ||
| Professional development programmes | |||||||
|---|---|---|---|---|---|---|---|
| Title of the Programme | Sponsoring Institution | Organising Institution | Association as | type | |||
| Communication and Presentation skills in Classroom Teaching | University of Delhi | Delhi University Computer Center and ICT Academy. | Attendee | Faculty Development Programmes | |||
| Online one week Faculty Development Programme on Academic Administration | Self Sponsor | Ramanujan College | Attending | Faculty Development Programmes | |||
| One-month Faculty Induction Programme | Self Sponsor | Ramanujan College | Attending | Orientation Programme | |||