Title Prof. First Name ALOK Last Name BHARTI
Designation Professor
Department Department of Zoology
Email acbharti@zoology.du.ac.in
Webpage
Phone.no +918800171246
Employement Info
Employee Type Nature Of Employment
Teaching Permanent
Educational Qualifications
Degree/Certification Name Institution Year of Completion
Ph.D. - Ph.D. Banaras Hindu University 1999
PG University of Delhi 1996
Certificate CSIR-UGC 1996
Certificate Ministry of Human Resource Development 1996
UG University of Delhi 1994
SSC Central Board of Secondary Education 1991
SSC Central Board of Secondary Education 1989
Fellowship Details
Name Of Fellowship Awarding Body Fellowship Level
INSA Young Scientist Medal in Basic and Applied Medical Sciences Indian National Science Academy (INSA) National
International Fellowship for Senior Scientist to visit CDC, Atlanta, USA Indian Council of Medical Research International
Indian National Science Academy (INSA)-DFG Bilateral Exchange Program at DKFZ Indian National Science Academy (INSA) International
INSA-CAS Bilateral Exchange Program to visit China Indian National Science Academy (INSA) International
Fellow Academies
Fellowship Academy Award Name Year Of Award
Council of Scientific and Industrial Research CSIR-NET-JRF 1996
Department of Education, MHRD Graduate Aptitude Test in Engineering (GATE) 1996
Teaching Experience (Within Institution)
Designation Duration
Professor Presently Working since 01-01-2016 (8 years, 9 months, 29 days)
Research Supervision Overview
PhD Scholars Supervised PhD Degrees Awarded Theses Submitted
5 17 0
M.Phil Scholars Supervised M.Phil Degrees Awarded M.Phil Theses Submitted
0 2 0
Research Publications
Title of Article Type of Publication Name of Journal ISSN Journal Volume Year Link to Article DOI (Digital Object Identifier)
Psoralidin: emerging biological activities of therapeutic benefits and its potential utility in cervical cancer Review Articles Exploration of Drug Science 2 2024 https://www.explorationpub.com/Journals/eds/Article/100863
Exosomal transcript cargo and functional correlation with HNSCC patients’ survival Research Papers in Peer Reviewed Journals BMC Cancer 24 2024 https://link.springer.com/article/10.1186/s12885-024-12759-9 https://doi.org/10.1186/s12885-024-12759-9
Prognostic and Therapeutic Potential of STAT3: Opportunities and Challenges in Targeting HPV-Mediated Cervical Carcinogenesis. Review Articles Critical Reviews in Oncology/Hematology 2024 https://www.sciencedirect.com/science/article/abs/pii/S1040842824000891?via%3Dihub 10.1016/j.critrevonc.2024.104346
Evidence that receptor activator of nuclear factor (NF)-kappaB ligand can suppress cell proliferation and induce apoptosis through activation of a NF-kappaB-independent and TRAF6-dependent mechanism. Research Papers in Peer Reviewed Journals Journal of Biological Chemistry 2024 https://www.sciencedirect.com/science/article/pii/S002192582074946X?via%3Dihub https://doi.org/10.1074/jbc.M308062200
Targeting Cervical Cancer Stem Cells by Phytochemicals. Review Articles Current Medicinal Chemistry 2024 https://www.eurekaselect.com/article/137994 10.2174/0109298673281823231222065616
3D tumor spheroids: morphological alterations a yardstick to anti-cancer drug response. Research Papers in Scopus Listed Journals Invitro Models 2023 https://link.springer.com/article/10.1007/s44164-023-00059-8 https://doi.org/10.1007/s44164-023-00059-8
In vivo antiangiogenic effect of nimbolide, trans-chalcone and piperine for use against glioblastoma. Research Papers in Peer Reviewed Journals BMC Cancer 2023 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691152/ 10.1186/s12885-023-11625-4
Anti-angiogenic Potential of Trans-chalcone in an In Vivo Chick Chorioallantoic Membrane Model: An ATP Antagonist to VEGFR with Predicted Blood-brain Barrier Permeability. Research Papers in Peer Reviewed Journals Cardiovascular & Hematological Agents in Medicinal Chemistry 2023 https://www.eurekaselect.com/article/135868 10.2174/0118715257250417231019102501
Phytochemicals Showing Antiangiogenic Effect in Pre-clinical Models and their Potential as an Alternative to Existing Therapeutics. Review Articles Current Topics in Medicinal Chemistry 2023 https://www.eurekaselect.com/article/135392 10.2174/0115680266264349231016094456
Evaluation of Therapeutic Potential of Selected Plant-Derived Homeopathic Medicines for their Action against Cervical Cancer Research Papers in Peer Reviewed Journals Homeopathy 2023 https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0042-1756436 10.1055/s-0042-1756436
Chick chorioallantoic membrane: a valuable 3D in vivo model for screening nanoformulations for tumor antiangiogenic therapeutics. The International Journal of Developmental Biology Review Articles International Journal of Developmental Biology 2023 https://ijdb.ehu.eus/article/230198pb 10.1387/ijdb.230198pb
Investigation of Molecular Mechanisms Underlying JAK/STAT Signaling Pathway in HPV-induced Cervical Carcinogenesis using ‘Omics’ Approach. Research Papers in Peer Reviewed Journals Medical Oncology 2022 https://link.springer.com/article/10.1007/s12032-022-01854-1 10.1007/s12032-022-01854-1
RNA Splicing: A Dual-edged Sword for Hepatocellular Carcinoma Review Articles Medical Oncology 2022 https://link.springer.com/article/10.1007/s12032-022-01726-8 10.1007/s12032-022-01726-8
Transcriptome analysis of cervical cancer exosomes and detection of HPVE6*I transcripts in exosomal RNA Research Papers in Peer Reviewed Journals BMC Cancer 2022 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8840784/ 10.1186/s12885-022-09262-4
Detection of human papillomavirus infection in oral cancers reported at dental facility: assessing the utility of FFPE tissues Research Papers in Peer Reviewed Journals Medical Oncology 2021 https://link.springer.com/article/10.1007/s12032-021-01608-5 10.1007/s12032-021-01608-5
Targeting Aberrant Expression of STAT3 and AP-1 Oncogenic Transcription Factors and HPV Oncoproteins in Cervical Cancer by Berberis aquifolium Research Papers in Peer Reviewed Journals Frontiers in Pharmacology 2021 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580881/ 10.3389/fphar.2021.757414
Phytochemicals as Potential Chemopreventive and Chemotherapeutic Agents for Emerging Human Papillomavirus-driven Head and Neck Cancers: Current Evidence and Future Prospects Review Articles Frontiers in Pharmacology 2021 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329252/ 10.3389/fphar.2021.699044
Exosomes from cervical cancer cells facilitate pro-angiogenic endothelial reconditioning through transfer of Hh signalling components Research Papers in Peer Reviewed Journals Cancer Cell International 2021 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223267/ 10.1186/s12935-021-02026-3
Tumor Reversion: a dream or a reality Review Articles Biomarker Research 2021 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101112/ 10.1186/s40364-021-00280-1
Human papillomavirus infection in head and neck cancers: Transcriptional triggers and changed disease patterns Review Articles Frontiers in Cellular and Infection Microbiology 2020 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738612/ 10.3389/fcimb.2020.537650
Delineating role of NF-κB and interacting cytokines during prostate cancer induced osteoclastogenesis. Research Papers in Peer Reviewed Journals Journal of Cellular Biochemistry 2020 https://onlinelibrary.wiley.com/doi/10.1002/jcb.29856 10.1002/jcb.29856
Level of phospho-STAT3 (Tyr705) correlates with copy number and physical state of human papillomavirus 16 genome in cervical precancer and cancer lesions. Research Papers in Peer Reviewed Journals PLoS One 2019 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728030/ 10.1371/journal.pone.0222089
Evaluation of Biomarkers p16/Ki-67 in Cervical Cytology for Diagnosis of Cervical Intraepithelial Neoplasia Research Papers in Scopus Listed Journals Indian Journal of Gynecologic Oncology 2019 https://onlinelibrary.wiley.com/doi/10.1002/prca.201900006 https://doi.org/10.1007/s40944-019-0290-5
Discovery of a novel connecting link between Renin‐Angiotensin System and cancer in Barrett's Esophagus by Proteomic screening. Review Articles PROTEOMICS–Clinical Applications 2019 https://onlinelibrary.wiley.com/doi/10.1002/prca.201900006 10.1002/prca.201900006
Upstream Hedgehog signaling components are exported in exosomes of cervical cancer cell lines Research Papers in Peer Reviewed Journals Nanomedicine 2018 https://www.tandfonline.com/doi/full/10.2217/nnm-2018-0143 10.2217/nnm-2018-0143
Constitutive activation and overexpression of NF-kappaB/c-Rel in conjunction with p50 contribute to aggressive tongue tumorigenesis. Research Papers in Peer Reviewed Journals Oncotarget 2018 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152474/ 10.18632/oncotarget.26041
Differentially Localized Survivin and STAT3 as Markers of Gastric Cancer Progression: Association with H. pylori Research Papers in Peer Reviewed Journals Cancer Reports 2018 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941477/ 10.1002/cnr2.1004
Chronic diseases, inflammation, and spices: how are they linked? Review Articles Journal of Translational Medicine 2018 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785894/ 10.1186/s12967-018-1381-2
miRNA as viral transcription tuners in HPV-mediated cervical carcinogenesis Review Articles Frontiers in Bioscience-Scholar 2018 https://www.imrpress.com/journal/FBS/10/1/10.2741/s499 10.2741/s499
Therapeutic strategies for human papillomavirus infection and associated cancers. Review Articles Frontiers in Bioscience-Elite 2018 https://www.imrpress.com/journal/FBE/10/1/10.2741/e808 10.2741/e808
Cervical Cancer Stem Cells Manifest Radioresistance: Association with Upregulated AP-1 Activity. Research Papers in Peer Reviewed Journals Scientific Reports 2017 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500478/ 10.1038/s41598-017-05162-x
Characterization of key transcription factors as molecular signatures of HPV-positive and HPV-negative oral cancers. Research Papers in Peer Reviewed Journals Cancer Medicine 2017 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345654/ 10.1002/cam4.983
Cross-talk between Human Papillomavirus Oncoproteins and Hedgehog Signaling Synergistically Promotes Stemness in Cervical Cancer Cells. Research Papers in Peer Reviewed Journals Scientific Reports 2016 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039669/ 10.1038/srep34377
HPV Inflammation Mediates IL-6 through STAT3 Signaling Pathway in Different Grades of Cervical Cancer Research Papers in Scopus Listed Journals Journal of Cancer Research and Molecular Medicine 2016 https://www.opensciencepublications.com/fulltextarticles/JCRMM-3-103.html
Cervical cancer stem cells selectively overexpress HPV oncoprotein E6 that controls stemness and self renewal through upregulation of HES1. Research Papers in Peer Reviewed Journals Clinical Cancer Research 2016 https://aacrjournals.org/clincancerres/article/22/16/4170/14943/Cervical-Cancer-Stem-Cells-Selectively-Overexpress 10.1158/1078-0432.CCR-15-2574
Human papillomavirus oncoproteins differentially modulate epithelial-mesenchymal transition in 5-FU-resistant cervical cancer cells. Research Papers in Peer Reviewed Journals Tumor Biology 2016 https://link.springer.com/article/10.1007/s13277-016-5143-6 10.1007/s13277-016-5143-6
Selective participation of c-Jun with Fra-2/c-Fos promotes aggressive tumor phenotypes and poor prognosis in tongue cancer. Research Papers in Peer Reviewed Journals Scientific Reports 2015 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652185/ 10.1038/srep16811
Berberine and Curcumin Target Survivin and STAT3 in Gastric Cancer Cells and Synergize Actions of Standard Chemotherapeutic 5-Fluorouracil. Research Papers in Peer Reviewed Journals Nutrition and Cancer 2015 https://www.tandfonline.com/doi/full/10.1080/01635581.2015.1085581 10.1080/01635581.2015.1085581
Alterations in microRNAs miR-21 and let-7a correlate with aberrant STAT3 signaling and downstream effects during cervical carcinogenesis. Research Papers in Peer Reviewed Journals Molecular Cancer 2015 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459448/ 10.1186/s12943-015-0385-2
Higher prevalence of human papillomavirus infection in adolescent and young adult girls belonging to different Indian tribes with varied socio-sexual lifestyle Research Papers in Peer Reviewed Journals PLoS One 2015 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425665/ 10.1371/journal.pone.0125693
Cervical cancer screening and treatment of cervical intraepithelial neoplasia in female sex workers using “screen and treat” approach Research Papers in Peer Reviewed Journals International Journal of Women's Health 2015 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427081/ 10.2147/IJWH.S80624
Folic Acid and Trastuzumab Functionalized Redox Responsive Polymersomes for Intracellular Doxorubicin Delivery in Breast Cancer. Research Papers in Peer Reviewed Journals Biomacromolecules 2015 https://pubs.acs.org/doi/10.1021/acs.biomac.5b00244 10.1021/acs.biomac.5b00244
Curcumin modulates cellular AP-1, NF-kB, and HPV16 E6 proteins in oral cancer Research Papers in Peer Reviewed Journals Ecancermedicalscience 2015 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407748/ 10.3332/ecancer.2015.525
Multifunctional ATRP based pH responsive polymeric nanoparticles for improved doxorubicin chemotherapy in breast cancer by proton sponge effect/endo-lysosomal escape. Research Papers in Scopus Listed Journals Polymer Chemistry 2015 https://pubs.rsc.org/en/content/articlelanding/2015/py/c4py01698j 10.1039/c4py01698j
Deregulation of microRNAs Let-7a and miR-21 Mediate Aberrant STAT3 Signaling during Human Papillomavirus-induced Cervical Carcinogenesis: Role of E6 Oncoprotein Research Papers in Peer Reviewed Journals BMC Cancer 2014 https://bmccancer.biomedcentral.com/articles/10.1186/1471-2407-14-996 10.1186/1471-2407-14-996
Carcinogenic Helicobacter pylori in gastric pre-cancer and cancer lesions: Association with tobacco-chewing. Research Papers in Peer Reviewed Journals World Journal of Gastroenterology 2014 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051925/ 10.3748/wjg.v20.i22.6860
Human Papillomavirus and control of cervical cancer in India. Review Articles Expert Review of Obstetrics & Gynecology 2014 https://www.tandfonline.com/doi/abs/10.1586/eog.10.23 https://doi.org/10.1586/eog.10.23
Functional regulatory role of STAT3 in HPV16-mediated cervical carcinogenesis. Research Papers in Peer Reviewed Journals PLoS One 2013 https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0067849 10.1371/journal.pone.0067849
Anticancer activity of Phyllanthus emblica Linn. (Indian gooseberry): Inhibition of transcription factor AP1 and HPV gene expression in cervical cancer cells. Research Papers in Peer Reviewed Journals Nutrition and Cancer 2013 https://www.tandfonline.com/doi/full/10.1080/01635581.2013.785008 10.1080/01635581.2013.785008
Preparation and in vitro evaluation of folate-receptor-targeted SPION-polymer micelle hybrids for MRI contrast enhancement in cancer imaging. Research Papers in Peer Reviewed Journals Nanotechnology 2012 https://iopscience.iop.org/article/10.1088/0957-4484/24/1/015603 10.1088/0957-4484/24/1/015603
Myelopotentiating effect of curcumin in tumor-bearing host: Role of bone marrow resident macrophages Research Papers in Peer Reviewed Journals Toxicology and Applied Pharmacology 2012 https://www.sciencedirect.com/science/article/pii/S0041008X12002633?via%3Dihub 10.1016/j.taap.2012.06.004
Effect of aspirin administration on reversal of tumor-induced suppression of myelopoiesis in T-cell lymphoma bearing host. Research Papers in Peer Reviewed Journals Blood Cells, Molecules, and Diseases 2012 https://www.sciencedirect.com/science/article/pii/S1079979612000599?via%3Dihub 10.1016/j.bcmd.2012.02.006
Oken. leaf on human cervical cancer cells Research Papers in Peer Reviewed Journals BMC Complementary and Alternate Medicine 2012 https://bmccomplementmedtherapies.biomedcentral.com/articles/10.1186/1472-6882-12-15 10.1186/1472-6882-12-15
Gender-specific antitumor action of aspirin in a murine model of a T-cell lymphoma bearing host Research Papers in Peer Reviewed Journals Blood Cells, Molecules and Diseases 2012 https://www.sciencedirect.com/science/article/pii/S1079979611001999?via%3Dihub 10.1016/j.bcmd.2011.10.006
Anti-neoplastic action of aspirin against a T cell lymphoma involves alteration in tumor microenvironment and regulation of tumor cell survival. Research Papers in Peer Reviewed Journals Biosciences Report 2011 https://portlandpress.com/bioscirep/article-abstract/32/1/91/55980/Anti-neoplastic-action-of-aspirin-against-a-T-cell?redirectedFrom=fulltext 10.1042/BSR20110027
Aberrant promoter methylation and loss of Suppressor of Cytokine Signalling-1 gene expression in the development of uterine cervical carcinogenesis. Research Papers in Peer Reviewed Journals Cellular Oncology (Dordr) 2011 https://link.springer.com/article/10.1007/s13402-011-0056-2 10.1007/s13402-011-0056-2
Berberine modulates AP-1 activity to suppress HPV transcription and downstream signaling to induce growth arrest and apoptosis in cervical cancer cells. Research Papers in Peer Reviewed Journals Molecular Cancer 2011 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098825/ 10.1186/1476-4598-10-
Efficacy of Plasma TGF-beta1 Level in Predicting Therapeutic Efficacy and Prognosis in Patients with Advanced Non-Small Cell Lung Cancer Research Papers in Peer Reviewed Journals Cancer Investigation 2011 https://www.tandfonline.com/doi/full/10.3109/07357907.2010.543208 10.3109/07357907.2010.543208
Breast cancer and human papillomavirus infection: No evidence of HPV etiology of breast cancer in Indian women Research Papers in Peer Reviewed Journals BMC Cancer 2011 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036645/ 10.1186/1471-2407-11-27
Application of a Multiplex PCR to cervical cells collected by a paper smear for the simultaneous detection of all mucosal human papillomaviruses and typing of HR HPV types 16 and 18. Research Papers in Peer Reviewed Journals Journal of Medical Microbiology 2010 https://www.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.019240-0#tab2 10.1099/jmm.0.019240-0
Aberrant expression and constitutive activation of STAT3 in cervical carcinogenesis: implications in high-risk human papillomavirus infection. Research Papers in Peer Reviewed Journals Molecular Cancer 2010 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984472/ 10.1186/1476-4598-9-282
Functional polymorphism of the MMP-1 promoter (-1607 1G/2G) in potentially malignant and malignant head and neck lesions in an Indian population. Research Papers in Peer Reviewed Journals Biomarkers 2010 https://www.tandfonline.com/doi/full/10.3109/1354750X.2010.511267 10.3109/1354750X.2010.511267
Comparative study between the Hybrid Capture II test and PCR based assay for the detection of human papillomavirus DNA in oral submucous fibrosis and oral squamous cell carcinoma. Research Papers in Peer Reviewed Journals Virology Journal 2010 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956722/ 10.1186/1743-422X-7-253
The 2010 global proficiency study of human papillomavirus genotyping in vaccinology Research Papers in Peer Reviewed Journals Journal of Clinical Microbiology 2010 https://journals.asm.org/doi/10.1128/jcm.00840-12?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed 10.1128/JCM.00840-12
Lack of utility of plasma TNF-α level in predicting therapeutic efficacy in patients with advanced non-small cell lung cancer. Research Papers in Peer Reviewed Journals Cytokine 2010 https://www.sciencedirect.com/science/article/pii/S1043466610001468?via%3Dihub 10.1016/j.cyto.2010.05.007
Utility of plasma TNF-α and TGF-β1 as predictors of survival and treatment outcome in advanced NSCLC. Research Papers in Peer Reviewed Journals Biomarkers 2010 https://www.tandfonline.com/doi/full/10.3109/1354750X.2010.485699 10.3109/1354750X.2010.485699
Synergistic effect of stromelysin-1 (matrix metalloproteinase-3) promoter (-1171 5A->6A) polymorphism in oral submucous fibrosis and head and neck lesions Research Papers in Peer Reviewed Journals BMC Cancer 2010 https://bmccancer.biomedcentral.com/articles/10.1186/1471-2407-10-369 10.1186/1471-2407-10-369
Clinical Relevance of Curcumin-induced Immunosuppression in Living-Related Donor Renal Transplant: An In Vitro Analysis Research Papers in Peer Reviewed Journals Journal of Clinical and Experimental Transplantation 2010 https://www.ectrx.org/forms/ectrxcontentshow.php?year=2010&volume=8&issue=2&supplement=0&makale_no=0&spage_number=161&content_type=FULL%20TEXT
Efficacy of circulating plasma DNA as a diagnostic tool for advanced non-small cell lung cancer and its predictive utility for survival and response to chemotherapy. Research Papers in Peer Reviewed Journals Lung Cancer 2010 https://www.sciencedirect.com/science/article/pii/S0169500210000644?via%3Dihub 10.1016/j.lungcan.2010.01.021
Trans-activation and expression patterns of jun and fos / AP-1 super-family proteins in human oral cancer. Research Papers in Peer Reviewed Journals International Journal of Cancer 2010 https://onlinelibrary.wiley.com/doi/10.1002/ijc.24807 10.1002/ijc.24807
Plasma DNA level in predicting therapeutic efficacy in advanced non-small cell lung cancer. Research Papers in Peer Reviewed Journals European Respiratory Journal 2010 https://erj.ersjournals.com/content/36/4/885.long 10.1183/09031936.00187909
Efficacy of plasma vascular endothelial growth factor in monitoring first-line chemotherapy in patients with advanced non-small cell lung cancer. Research Papers in Peer Reviewed Journals BMC Cancer 2009 https://bmccancer.biomedcentral.com/articles/10.1186/1471-2407-9-421 10.1186/1471-2407-9-421
Transcription factor AP-1 in esophageal squamous cell carcinoma: Alterations in activity and expression during Human Papillomavirus infection Research Papers in Peer Reviewed Journals BMC Cancer 2009 https://bmccancer.biomedcentral.com/articles/10.1186/1471-2407-9-329 10.1186/1471-2407-9-329
Human papillomavirus & cervical cancer: looking ahead. Review Articles Indian Journal of Medical Research 2009 https://journals.lww.com/ijmr/citation/2009/30030/Human_papillomavirus___cervical_cancer__Looking.2.aspx
Human Papillomaviruses Infections in Cancers of Different Human Organ Sites Review Articles Indian Journal of Medical Research 2009 https://journals.lww.com/ijmr/abstract/2009/30030/infection_of_human_papillomaviruses_in_cancers_of.5.aspx
Anti HPV Therapeutics: Facts and Future. Review Articles Indian Journal of Medical Research 2009
Elimination of high-risk human papillomavirus type HPV16 infection by 'Praneem' polyherbal tablet in women with early cervical intraepithelial lesion Research Papers in Peer Reviewed Journals Journal of Cancer Research and Clinical Oncology 2009 https://link.springer.com/article/10.1007/s00432-009-0617-1 10.1007/s00432-009-0617-1 Full text linksCite
Aberrant promoter methylation and reduced expression of p16 gene in esophageal squamous cell carcinoma from Kashmir valley: a high-risk area Research Papers in Peer Reviewed Journals Molecular and Cellular Biochemistry 2009 https://link.springer.com/article/10.1007/s11010-009-0173-7 10.1007/s11010-009-0173-7
Overexpression of STAT3 in HPV-mediated cervical cancer in a north Indian population. Research Papers in Peer Reviewed Journals Molecular and Cellular Biochemistry 2009 https://link.springer.com/article/10.1007/s11010-009-0133-2 10.1007/s11010-009-0133-2
Surface Engineered Dendrimers for Dual Drug Delivery: A receptor Up-regulation and Enhanced Cancer Targeting Strategy. Research Papers in Peer Reviewed Journals Journal of Drug Targeting 2008 https://www.tandfonline.com/doi/full/10.1080/10611860802473154 10.1080/10611860802473154
Differential expression and activation of NF-B family proteins during oral carcinogenesis: Role of high risk human papillomavirus infection. Research Papers in Peer Reviewed Journals International Journal of Cancer 2006 https://onlinelibrary.wiley.com/doi/10.1002/ijc.22262 10.1002/ijc.22262
Curcumin (Diferuloylmethane) inhibits receptor activator of NF-kappaB ligand-induced NF-kappaB activation in osteoclast precursors and suppresses osteoclastogenesis. Research Papers in Peer Reviewed Journals Journal of Immunology 2004 10.4049/jimmunol.172.10.5940
Induction of cell cycle arrest and apoptosis by the proteasome inhibitor PS-341 in Hodgkin disease cell lines is independent of inhibitor of nuclear factor-B mutations or activation of the CD30, CD40, and RANK receptors. Research Papers in Peer Reviewed Journals Clinical Cancer Research 2004 https://aacrjournals.org/clincancerres/article/20/11/3044/78450/Correction-Induction-of-Cell-Cycle-Arrest-and https://doi.org/10.1158/1078-0432.CCR-14-1017
Nuclear factor-kappaB and STAT3 are constitutively active in CD138+ cells derived from multiple myeloma patients, and suppression of these transcription factors leads to apoptosis Research Papers in Peer Reviewed Journals Blood 2004 10.1182/blood-2003-06-2151
Curcumin (Diferuloylmethane) inhibits constitutive and interleukin-6-inducible STAT3 phosphorylation in human multiple myeloma cells: Relationship to Suppression of proliferation Research Papers in Peer Reviewed Journals Journal of Immunology 2003 https://journals.aai.org/jimmunol/article/171/7/3863/71539/Curcumin-Diferuloylmethane-Inhibits-Constitutive 10.4049/jimmunol.171.7.3863
Curcumin (diferuloylmethane) downregulates the constitutive activation of nuclear factor-kappaB and IkappaB alpha kinase in human multiple myeloma cells leading to suppression of proliferation and induction of apoptosis. Research Papers in Peer Reviewed Journals Blood 2003 https://ashpublications.org/blood/article/101/3/1053/88833/Curcumin-diferuloylmethane-down-regulates-the https://doi.org/10.1182/blood-2002-05-1320
Anticancer Potential of Curcumin: Preclinical and Clinical Studies. Review Articles Anticancer Research 2003
Chemopreventive agents induce suppression of nuclear factor-kappa B leading to chemosensitization Research Papers in Peer Reviewed Journals Annals of the New York Academy of Sciences 2002 https://nyaspubs.onlinelibrary.wiley.com/doi/full/10.1111/j.1749-6632.2002.tb04671.x?sid=nlm%3Apubmed 10.1111/j.1749-6632.2002.tb04671.x Full text linksCite
The Role of TNF and its family members in inflammation and cancer: lessons from gene deletion Book Reviews Current Drug Targets: Inflammation and Allergy 2002 10.2174/1568010023344571
Nuclear factor-kappa B and cancer: its role in prevention and therapy. Review Articles Biochemical Pharmacology 2002 https://doi.org/10.1016/S0006-2952(02)01154-1
Trans-3,4,3’,5’-tetrahydroxystilbene (piceatannol) inhibits TNF-induced nuclear Factor-kappaB activation through suppression of IkappaB alpha kinase and p65 phosphorylation Research Papers in Peer Reviewed Journals Journal of Immunology 2001 https://journals.aai.org/jimmunol/article/169/11/6490/74596/Piceatannol-Inhibits-TNF-Induced-NF-B-Activation 10.4049/jimmunol.169.11.6490
Induction of apoptosis in bone marrow cells by gangliosides produced by a T cell lymphoma Research Papers in Peer Reviewed Journals Immunology Letters 2000 https://www.sciencedirect.com/science/article/pii/S0165247800001565?via%3Dihub 10.1016/s0165-2478(00)00156-5
Gangliosides derived from a T cell lymphoma inhibit bone marrow cell proliferation and differentiation Research Papers in Peer Reviewed Journals International Immunopharmacology 2001 https://www.sciencedirect.com/science/article/pii/S1567576900000047?via%3Dihub 10.1016/s1567-5769(00)00004-7
Inhibition of macrophage nitric oxide production by gangliosides derived from T cell lymphoma: Involved mechanism(s) Research Papers in Peer Reviewed Journals Nitric oxide: Biology and Chemistry 2003 Inhibition of macrophage nitric oxide production by gangliosides derived from T cell lymphoma: Involved mechanism(s)
Ranking the role of RANK ligand in apoptosis Review Articles Apoptosis 2004 10.1023/B:APPT.0000045780.10463.c6
Expression Genomics: Deciphering the Molecular Signature of Genes in Pathogenesis of Cervical Cancer Research Papers in Web of Science Listed Journals Perspectives in Cytology and Genetics 2007
Plasma nucleosome levels might predict response to therapy in patients with advanced non-small-cell lung cancer. Research Papers in Peer Reviewed Journals Clinical Lung Cancer 2010 https://www.sciencedirect.com/science/article/abs/pii/S1525730411700365?via%3Dihub 10.3816/CLC.2010.n.006
Genetic polymorphisms of matrix metalloproteinases and their inhibitors in potentially malignant and malignant lesions of the head and neck. Review Articles Journal of Biomedical Sciences 2010 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846899/ 10.1186/1423-0127-17-10
Global proficiency study of human papillomavirus genotyping Research Papers in Peer Reviewed Journals Journal of Clinical Microbiology 2010 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020877/ 10.1128/JCM.00918-10
Prevalence of human papillomavirus and co-existent sexually transmitted infections among female sex workers, men having sex with men and injectable drug abusers from eastern India. Research Papers in Peer Reviewed Journals Asian Pacific Journal of Cancer Prevention 2012 https://journal.waocp.org/?sid=Entrez:PubMed&id=pmid:22631651&key=2012.13.3.799 10.7314/apjcp.2012.13.3.799
Clearance of cervical Human Papillomavirus by topical application of curcumin and curcumin containing polyherbal cream: a phase II randomized controlled study Research Papers in Peer Reviewed Journals Asian Pacific Journal of Cancer Prevention 2013 https://journal.waocp.org/?sid=Entrez:PubMed&id=pmid:24289574&key=2013.14.10.5753 10.7314/apjcp.2013.14.10.5753
Physical state and copy number of high risk Human Papillomavirus type 16 DNA in the progression of cervical cancer. Research Papers in Peer Reviewed Journals Indian Journal of Medical Research 2014 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078491/
Expression of BRCA1 and BRCA2 proteins and their correlation with clinical staging in breast cancer. Research Papers in Peer Reviewed Journals Journal of Cancer Research and Therapeutics 2015 https://journals.lww.com/cancerjournal/fulltext/2015/11010/expression_of_brca1_and_brca2_proteins_and_their.30.aspx 10.4103/0973-1482.140985
BASANT, a Polyherbal Safe Microbicide Eliminates HPV-16 in Women with Early Cervical Intraepithelial Lesions. Research Papers in Scopus Listed Journals Journal of Cancer Therapy 2015 https://www.scirp.org/journal/paperinformation?paperid=61684 10.4236/jct.2015.614126
Physical interaction between STAT3 and AP1 in cervical carcinogenesis: Implications in HPV transcription control Research Papers in Peer Reviewed Journals Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 2023 https://www.sciencedirect.com/science/article/pii/S0925443923001837?via%3Dihub 10.1016/j.bbadis.2023.166817
Non-Journal Publications
Title of Publication Type of Publication Publisher Role ISBN Year Link to Publication Level
Circulating Tumor Cells: A New Avenue for Clinical Management of Cervical Cancer. Socio-Scientific Interaction in Diabetes and Cancer and Its Management. Chapters in Books BP International Co-Author 2023 International
Role of angiotensin in different malignancies Chapters in Books Elsevier, USA Co-Author 2023 International
Role of Exosomes in Tumor Induced Neo-Angiogenesis, Chapters in Books InTech Open. Co-Author 2022 International
Need for a better cervical cancer screening tool for ‘elimination’ of cervical cancer, I Chapters in Books SSRF Newsletter Co-Author 2019 International
Role of Nutraceuticals in Chemoresistance to Cancer Edited/Translated Books Elsevier, USA Editor 2017 International
Micro RNA-based Regulation during HPV Infection and Cervical Carcinogenesis: Where Do We Stand? Chapters in Books Narendra Publishing House, Delhi, India, Co-Author 2017 National
Pathways Linked to Cancer Chemoresistance and Their Targeting by Nutraceuticals. Chapters in Books Elsevier, USA. Co-Author 2017 International
Berberine as an Adjuvant and Sensitizer to Current Chemotherapy. Chapters in Books Elsevier, USA. Co-Author 2017 International
Therapeutic startegies for human papillomavirus infection and associated cancers. Chapters in Books Frontiers in Biosciences. Co-Author 2017 International
MiRNA as Viral Transcription Tuners in HPV-mediated Cervical Carcinogenesis Chapters in Books Frontiers in Biosciences. Co-Author 2017 International
Cervical Cancer Stem Cells and Their Association with Human Papillomavirus: Are They Ready as Anticancer Targets? Multi-Targeted Approach to Treatment of Cancer Chapters in Books Switzerland, Springer International Publishing Co-Author 2015 International
Chapter 9: Emerging Phytochemicals for Prevention & Treatment of Cancers. Chapters in Books All India Institute of Medical Sciences, New Delhi, Ranbaxy Science Foundation Co-Author 2014 National
Chapter 7: Natural Dietary Compounds for Cancer Chemoprevention: Targeting of Cancer Stem Cells. Chapters in Books All India Institute of Medical Sciences, New Delhi, Ranbaxy Science Foundation Co-Author 2014 National
Human Papillomavirus Detection Methods. Cervical Cytopathology. Chapters in Books S. Bhambhani. New Delhi, Mehta Press. Co-Author 2012 National
Cervical Cancer, HPV Infection and its Genotypes in India: Prospects of Prevention Strategies. Chapters in Books ISSRF Newsletter. Jaipur, India, ISSRF Co-Author 2012 National
WHO QSS (2010). Human Papillomavirus Laboratory Manual (First Edition). Geneva, World Health Organization. Chapters in Books WHO Co-Author 2010 International
“Elimination of HPV and control viral oncogene expression in cervical cells by herbal compounds”, Chapters in Books Narosa Publishing House Co-Author 2009 National
Chapter 2 – Tumor Necrosis Factor and its Family Members. Chapters in Books Ed. Pasqualini, R., Arap Co-Author 2009 National
Bharti, A.C., (2008). Stem Cell Research in India. Chapters in Books Cancer News 2 (Sept) Co-Author 2008 National
Infections Causing Cancer. Chapters in Books UICC Press, Geneva, Switzerland Co-Author 2006 International
PARP Cleavage and Caspase Activity to Assess Chemosensitivity. Chapters in Books Humana Press, NJ, USA Co-Author 2005 International
Therapeutic Potential of Curcumin Derived from Turmeric (Curcuma longa). Chapters in Books Eds. Packer, L., Nam Ong, C. and Halliwell, B Co-Author 2004 National
Research Projects
Project Title Project Type Year Of Sanction Outcome/Output Duration
Investigation of Host-transcription factors that predispose Head and Neck cancer to HPV16 infection Major 2015 01-02-2016 To 27-05-2019 (3 years, 3 months, 26 days)
Investigation of molecular mechanisms of STAT3-mediated regulation of HPV infection and cervical carcinogenesis Major 2017 01-01-2018 To 31-12-2021 (3 years, 11 months, 30 days)
Investigation of role of exosomes in cervical cancer angiogenesis Major 2018 19-11-2018 To 18-04-2022 (3 years, 4 months, 30 days)
Identification of Homeopathic formulations with anti-cervical cancer and anti-HPV activity Major 2021 01-01-2021 To 31-12-2022 (1 years, 11 months, 30 days)
Development of stem cell targeted therapy against cervical cancer Minor 2021 01-11-2021 To 31-03-2022 (4 months, 30 days)
STAT3-HPV Flow-FISH: Development of innovative single molecule RNA (smRNA) detection, flowcytometry-based quantitative and diagnostic assay for detection of transcriptionally active high risk HPV infection Major 2021 Ongoing since 01-01-2022 (2 years, 9 months, 29 days)
Circulating tumour cells in cervical cancer: identification, characterisation, and prognostic evaluation in predicting distant metastasis by "Omics" approach Major 2023 Ongoing since 16-10-2023 (1 years, 14 days)
Identification of novel phytochemical with cancer stem cell targeting potential against cervical cancer Minor 2022 01-09-2022 To 31-03-2023 (6 months, 30 days)
Identification of anti-cervical cancer stem cell activity of Psoralidin and Sanguinarine Minor 2023 01-09-2023 To 31-03-2024 (6 months, 30 days)
Effectiveness of add-on homeopathy in treatment of Type II diabetes with or without complications: A multicentric pragmatic double-blind randomised controlled trial (Telomerase) Major 2023 16-08-2023 To 22-02-2024 (6 months, 6 days)
Identification of Homeopathic formulations with anti-cervical cancer and anti-HPV activity Phase II Major 2024 Ongoing since 17-05-2024 (5 months, 13 days)
Assessment of Anti-cervical Cancer Stem Cell Activity of Morusin Minor 2024 Ongoing since 01-09-2024 (1 months, 29 days)
Professional Development Programmes
Programme Title Sponsoring Institution Organizing Institution Role Type of Programme
Advancement in Life Sciences leading to improvement in Agriculture environment and Human Health Centre for Professional Development in Higher Education (CPDHE), UGC Human Resource Development Centre University of Delhi Organizer Refresher Program
Honors and Awards
Name of the Award Awarding Body Award Category Level Award Date
Travel Award International Union of Immunology Societies, Department of Science and Technology and Talwar Research Foundation Academic International 05-07-2004
INSA Medal for Young Scientists in Basic and Applied Medical Sciences Indian National Science Academy (INSA) Academic National 09-12-2009
ICMR-International Fellowship for Senior Scientists for training to visit CDC, Atlanta, USA Indian Council for Medical Research Research International 01-01-2013
INSA-DFG Bilateral Exchange program (Senior Scientist) for 3 weeks at DKFZ. Indian National Science Academy (INSA) Research International 01-01-2013
INSA-CAS Bilateral Exchange program (Senior Scientist) for 2 weeks to visit China. Indian National Science Academy (INSA) Research International 09-12-2009
Talk Poster Presented
Name of the Activity Role Date of Activity
Invited to deliver a talk on New Horizons in HPV diagnostics: Integration of HPV on STD Chip Speaker 02-12-2006
Transcriptional Targeting of STAT3 in Cervical Carcinogenesis by Herbal Derivatives Speaker 09-09-2007
Delivered a lecture on “Cancer Stem Cells: Role in Cervical Cancer Development and Progression Speaker 29-07-2008
Suppression of Activated STAT3 Induces p53 Accumulation and Leads to Apoptosis of Cervical Cancer Cells Speaker 03-11-2008
Dry ‘Paper Smear’ Method for Rapid HPV Testing Panelist 17-11-2008
Finding Cancer Stem Cells in Cancer of the Uterine Cervix: Challenges and Opportunities Speaker 28-02-2009
Tumor Immunology Speaker 23-03-2009
Regional HPV Laboratory for South East Asia Under WHO Global HPV Laboratory Network (HPV LabNet) Speaker 26-04-2009
Human Papillomavirus and Cancer : Carcinogenic link beyond cervical cancer Participant 01-08-2009
Role of Transcription Factor STAT3 in Cervical Carcinogenesis Speaker 14-10-2010
PGMY- Reverse Line Blot- A Comprehensive HPV Genotyping Assay & its utility in STI Research in India Speaker 02-11-2011
HPV in Men: Prevalence and Natural History Speaker 04-11-2011
Advances in Anti-Human Papillomavirus Therapeutics Speaker 08-02-2012
microRNA-Mediated Regulation of STAT3 activity in HPV-induced Cervical Carcinogenesis Speaker 04-03-2012
Survivin as Marker of Gastric Cancer Progression and Target for Overcoming Chemoresistance Speaker 17-11-2012
Role of Transcription Factor STAT3 in Linking HPV Infection with Cervical Carcinogenesis Speaker 22-12-2012
Transcriptional Regulation of HR-HPV16 and Anti-HPV Therapeutics Speaker 09-01-2013
Role of Transcription Factor STAT3 in Linking HPV Infection with Cervical Carcinogenesis Speaker 16-02-2013
Flowcytometry and cell sorting in molecular oncology Speaker 19-07-2013
Transcriptional Control of Human Papillomavirus Infection in Malignant Transformation Speaker 22-10-2013
Herbal Derivatives as Anti-Cancer Therapeutics Speaker 16-11-2013
Anti-cancer Phytochemicals: Molecular Targets and Downstream Effects on Cell Cycle and Apoptosis Speaker 30-11-2013
Role of Human Papillomavirus Infection in Maintenance of Cervical Cancer Stem Cells: Targeting by Curcumin Speaker 08-02-2014
Host Transcription Factors as Cofactors of Cervical Carcinogenesis: Role of STAT3 Speaker 14-09-2014
Role of Viral Oncoproteins in Maintenance of Cervical Cancer Stem Cells Speaker 09-11-2014
Transcriptional Regulation in Control of HPV infection and Associated Malignancies Speaker 01-12-2014
Cervical Cancer and HPV Infection: Targeting Cancer Stem Cells and Radio-resistance by Curcumin Speaker 12-12-2012
Anti-HPV Therapeutics: Bottlenecks and Future of Emerging Leads Speaker 19-02-2015
MicroRNA-mediated Regulatory Loops Promote Carcinogenic Signaling in Cervical Cancer Speaker 28-08-2015
Human Papillomavirus Oncogenes Differentially Modulate Chemoresistance in Cervical Cancer Cells Speaker 02-11-2015
HPV Viral Oncoproteins: Role Beyond Cervical Cancer Initiation and Progression Speaker 10-04-2016
Targeting Human Papillomavirus Infection and Cervical Cancer by Herbal Derivatives Speaker 09-09-2016
Oral HPV Infections: Are They Different from Genital Infections”, Workshop on “Cervical Cytology and its Integration with HPV Detection Speaker 14-10-2016
Epidemiology of HPV Types Amongst General Population And Genital Cancer Speaker 15-10-2016
Cervical Cancer - a Preventable Cancer but Not Yet Prevented: Avenues for Surgical Strike Speaker 26-11-2016
Role of Viral Oncoproteins in Maintenance of Cervical Cancer Stem Cells and Chemoresistance Speaker 22-01-2017
Methods of HPV Testing- Practical Aspects Speaker 03-03-2017
Maintenance of Cervical Cancer Stem Cells and Chemoresistance: Viral Oncoproteins as Potential Therapeutic Targets Speaker 31-03-2017
Targeting Radioresistance in Cervical Cancer by Curcumin through Combating AP-1 Activity in Cancer Stem Cells Speaker 02-09-2017
HPV infection, Cervical Cytology & Cervical Carcinogenesis: Basics Speaker 08-09-2017
Molecular Methods of HPV Testing in Cervical Scrapes: Options and Opportunities Speaker 08-09-2017
Cervical Cancer – A Preventable Lifestyle Disease but NOT YET Prevented: Molecular Targets as Avenues for Potential Therapeutics Speaker 01-02-2018
Targeting Radioresistance in Cervical Cancer by Curcumin through Combating AP-1 Activity in Cancer Stem Cells Speaker 13-02-2018
Role of Viral Oncoproteins in Maintenance of Cervical Cancer Stem Cells and Chemoresistance Speaker 10-04-2018
Cervical Cancer – a success story from an immunologist viewpoint: Even a small star shines in the dark Speaker 11-05-2018
STAT3: is it a master regulator or prime target of virally-induced tumors? Speaker 31-08-2018
“HPV and Cervical Cancer Stem Cells: Viral Oncoproteins as Causative Link and Promoter of Chemoresistance Speaker 07-09-2018
Anti-Cervical Cancer and Anti-HPV Activity of Nutraceuticals & Plant Derived Homoeopathic Formulations Speaker 15-09-2018
Viral Oncoproteins as Regulators of Cervical Cancer Stem Cells and Chemo/Radio-resistance Speaker 29-12-2018
Exploration of Exosomal Cargo from Cervical Cancer Cells and its Functional Relevance Speaker 09-02-2019
STAT3: A master regulator or prime target of HPV-induced tumorigenesis Speaker 01-03-2019
Role of Exosomes in Carcinogenic Signaling in Cervical Cancer Speaker 11-09-2019
Potential of Repurposing homeopathic formulations based on Berberis vulgaris and Berberis aquifolium in treatment of cervical cancer Speaker 24-09-2019
Activated STAT3 signaling in cervical carcinogenesis: its role in HPV transcription, replication and integration in the host genome Speaker 14-02-2020
Human Papillomavirus Infection and Cervical Cancer: Challenges and Opportunities for Early Detection and Prevention Speaker 15-02-2020
Exploration of exosomal cargo with implications in tumor progression of squamous cell carcinoma harbouring Human papillomavirus infection Speaker 18-02-2018
Role of Inflammation and Immune System for Cancer Prevention and Treatment Speaker 13-02-2020
Elimination of Cervical Cancer: From Research to Practice Speaker 04-12-2021
Cancer Biology: Advances and Challenges’ Speaker 11-11-2021
Host virus interactions during cervical cancer development: mechanisms, challenges and opportunities Speaker 21-01-2021
Translational Chemoprevention and Brainstorming Speaker 18-11-2022
Recent Trends in Animal Sciences (RTAS) Speaker 25-03-2022
Combating Cancer: Biology to Therapy to Drug Resistance Speaker 02-03-2022
Applications of Animal Culture Techniques in Cancer Research Speaker 19-09-2022
Circulating Tumor Cells: Adding New Dimensions to Cancer Detection and Management Speaker 20-05-2023
In vivo Antiangiogenic Effect of Nimbolide, Trans-chalcone and Piperine for use against Glioblastoma Speaker 23-02-2024
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