Title Prof. First Name Amit Last Name Dutt
Designation Professor
Department Department of Genetics SDC
Email amitdutt@south.du.ac.in
Webpage https://www.actrec.gov.in/pi-webpages/AmitDutt/dutt_index.html
Phone.no 24117399
Employement Info
Employee Type Nature Of Employment
Teaching Permanent
Educational Qualifications
Degree/Certification Name Institution Year of Completion
Ph.D. - Ph.D Zurich University 2004
Ph.D. - Ph.D ICGEB, New Delhi 2000
PG Jamia Millia Islamia, University, New Delhi 1997
Diploma Sri Venkateshwara Collage, University of Delhi, New Delhi 1995
UG University of Delhi, New Delhi 1994
HSC CBSE Board/DTEA Sr Secondary School, R.K. Puram, New Delhi 1991
SSC CBSE Board/DTEA Sr Secondary School, R.K. Puram, New Delhi 1989
Fellowship Details
Name Of Fellowship Awarding Body Fellowship Level
Tata Innovation Award Fellowship Department of Biotechnology National
Fellow Academies
Fellowship Academy Award Name Year Of Award
Shanti Swarup Bhatnagar Prize Shanti Swarup Bhatnagar Prize 2017
Research Publications
Title of Article Type of Publication Name of Journal ISSN Journal Volume Year Link to Article DOI (Digital Object Identifier)
Genomic characterization of tobacco/nut chewing HPV-negative early stage tongue tumors identify MMP10 asa candidate to predict metastases Research Papers in Peer Reviewed Journals Oral Oncology 1368-8375. 73 2017 https://pubmed.ncbi.nlm.nih.gov/28939077/ DOI: 10.1016/j.oraloncology.2017.08.003
Development and characterization of a patient‑derived orthotopic xenograft of therapy‑resistant breast cancer Research Papers in Peer Reviewed Journals Oncology Reports 1021-335X 49 2023 https://pubmed.ncbi.nlm.nih.gov/36999625/ DOI: 10.3892/or.2023.8536
Role of miR-944/MMP10/AXL- axis in lymph node metastasis in tongue cancer Research Papers in Peer Reviewed Journals Communications Biology 2399-3642 6 2023 https://pubmed.ncbi.nlm.nih.gov/36650344/ DOI: 10.1038/s42003-023-04437-6
Immunohistochemical expression of H3.3 G34W in 100 giant cell tumors of bone and its diagnostic mimics, including its value in resolving uncommon diagnostic scenarios: A single institutional study at a tertiary cancer referral center, India Research Papers in Peer Reviewed Journals Indian Journal of Pathology and Microbiology 0377-4929 8 2023 https://pubmed.ncbi.nlm.nih.gov/38391356/ DOI: 10.4103/ijpm.ijpm_886_23
Real-World Evidence of EGFR Targeted Therapy in NSCLC- A Brief Report of Decade Long Single Center Experience Research Papers in Peer Reviewed Journals JTO Clinical Research Reports 2666-2479 4 2023 https://pubmed.ncbi.nlm.nih.gov/38033811/ https://doi.org/10.1016/j.jtocrr.2023.100566
Mitocurcumin utilizes oxidative stress to upregulate JNK/p38 signaling and overcomes Cytarabine resistance in acute myeloid leukemia Research Papers in Peer Reviewed Journals Cellular signalling 0898-6568 114 2023 https://pubmed.ncbi.nlm.nih.gov/38048856/ https://doi.org/10.1016/j.cellsig.2023.111004
Association of Cutibacterium acnes with human thyroid cancer Research Papers in Peer Reviewed Journals Frontiers in Endocrinology (Lausanne) 1664-2392. 14 2023 https://pubmed.ncbi.nlm.nih.gov/38027096/ https://doi.org/10.3389/fendo.2023.1152514
Inhibition of PERK mediated UPR acts as a switch for reversal of residual senescence and as senolytic therapy in glioblastoma Research Papers in Peer Reviewed Journals Neuro Oncol. 1523-5866 134 2023 https://pubmed.ncbi.nlm.nih.gov/39021199/ doi: 10.1093/neuonc/noae134
Immunohistochemical expression of H3.3 G34W in 100 giant cell tumors of bone and its diagnostic mimics, including its value in resolving uncommon diagnostic scenarios: A single institutional study at a tertiary cancer referral center, India Research Papers in Peer Reviewed Journals Indian Journal of Pathology and Microbiology 0377-4929 8 2023 https://pubmed.ncbi.nlm.nih.gov/38391356/ DOI: 10.4103/ijpm.ijpm_886_23
Utility of immunohistochemical expression of H3.3K36M and DOG1 in the diagnosis of chondroblastomas: An experience from a tertiary cancer referral center Research Papers in Peer Reviewed Journals Annals of Diagnostic Pathology 1092-9134 66 2023 https://pubmed.ncbi.nlm.nih.gov/37356274/ doi: 10.1016/j.anndiagpath.2023.152174
Singleton mutations in large-scale cancer genome studies: uncovering the tail of cancer genome Research Papers in Peer Reviewed Journals NAR Cancer 2603-9299 6 2023 https://academic.oup.com/narcancer/article/6/1/zcae010/7626437 https://doi.org/10.1093/narcan/zcae010
Utility of immunohistochemical expression of H3.3K36M and DOG1 in the diagnosis of chondroblastomas: An experience from a tertiary cancer referral center Research Papers in Peer Reviewed Journals Annals of Diagnostic Pathology 1092-9134 66 2023 https://pubmed.ncbi.nlm.nih.gov/37356274/ doi: 10.1016/j.anndiagpath.2023.152174
RET Alterations Differentiate Molecular Profile of Medullary Thyroid Cancer Research Papers in Peer Reviewed Journals JCO Precis Oncol 2473-4284 8 2023 https://pubmed.ncbi.nlm.nih.gov/38754058/ doi: 10.1200/PO.23.00622
Recurrent UBE3C-LRP5 translocations in head and neck cancer with therapeutic implications Research Papers in Peer Reviewed Journals npj Precision Oncology 2515-1354 8 2023 https://www.nature.com/articles/s41698-024-00555-4 doi.org/10.1038/s41698-024-00555-4
Surgical Tumor Resection Deregulates Hallmarks of Cancer in Resected Tissue and the Surrounding Microenvironment Research Papers in Peer Reviewed Journals Mol Cancer Res 1541-7786 22 2023 https://pubmed.ncbi.nlm.nih.gov/38394149/ https://doi.org/10.1158/1541-7786.MCR-23-0265
Real-World Evidence of EGFR Targeted Therapy in NSCLC- A Brief Report of Decade Long Single Center Experience Research Papers in Peer Reviewed Journals JTO Clinical Research Reports 2666-2479 4 2023 https://pubmed.ncbi.nlm.nih.gov/38033811/ https://doi.org/10.1016/j.jtocrr.2023.100566
Deciphering the mechanisms of action of progesterone in breast cancer Review Articles Oncotarget 1949-2553 14 2023 https://pubmed.ncbi.nlm.nih.gov/37395734/ https://doi.org/10.18632/oncotarget.28455
Novel covalent CDK7 inhibitor potently induces apoptosis in acute myeloid leukemia and synergizes with Venetoclax Research Papers in Peer Reviewed Journals Journal of Experimental & Clinical Cancer Research 1756-9966 42 2023 https://pubmed.ncbi.nlm.nih.gov/37507802/ DOI: 10.1186/s13046-023-02750-w
A Rare Case of A Low-Grade Inflammatory Leiomyosarcoma/Histiocyte-Rich Rhabdomyoblastic Tumor in the Neck of An Adolescent Male Research Papers in Peer Reviewed Journals Turkish Journal of Pathology (Turk Patoloji Derg) 1018-5615 39 2023 https://pubmed.ncbi.nlm.nih.gov/35642345/ DOI: 10.5146/tjpath.2022.01577
Inhibition of PERK mediated UPR acts as a switch for reversal of residual senescence and as senolytic therapy in glioblastoma Research Papers in Peer Reviewed Journals Neuro Oncol. 1523-5866 134 2023 https://pubmed.ncbi.nlm.nih.gov/39021199/ doi: 10.1093/neuonc/noae134
Deciphering the mechanisms of action of progesterone in breast cancer Review Articles Oncotarget 1949-2553 14 2023 https://pubmed.ncbi.nlm.nih.gov/37395734/ https://doi.org/10.18632/oncotarget.28455
Integrated genomics approach to identify biologically relevant alterations in fewer samples Research Papers in Peer Reviewed Journals BMC Genomics 1471-2164. 16 2016 https://pubmed.ncbi.nlm.nih.gov/26572163/ DOI: 10.1186/s12864-015-2138-4
Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer Research Papers in Peer Reviewed Journals Cancer Discovery 2159-8274. 1 2012 https://pubmed.ncbi.nlm.nih.gov/22328973/ DOI: 10.1158/2159-8274.CD-11-0005
Osimertinib for lung cancer cells harboring low-frequency EGFR T790M mutation Research Papers in Peer Reviewed Journals Translational Oncology 1936-5233 22 2023 https://pubmed.ncbi.nlm.nih.gov/35653897/ DOI: 10.1016/j.tranon.2022.101461
Drug-sensitive FGFR3 mutations in lung adenocarcinoma Research Papers in Peer Reviewed Journals Annals of Oncology 0923-7534. 28 2018 https://pubmed.ncbi.nlm.nih.gov/27998968/ DOI: 10.1093/annonc/mdw636
Progesterone modulates the DSCAM-AS1/miR-130a/ESR1 axis to suppress cell invasion and migration in breast cancer Research Papers in Peer Reviewed Journals Breast Cancer Research 1465-5411 24 2023 https://pubmed.ncbi.nlm.nih.gov/36578092/ DOI: 10.1186/s13058-022-01597-x
A preliminary investigation demonstrating the effect of quercetin on the expression of genes related to cell-cycle arrest, apoptosis and xenobiotic metabolism in human CO115 colon-adenocarcinoma cells using DNA microarray Research Papers in Peer Reviewed Journals Biotechnology and Applied Biochemistry 0885-4513 45 2007 https://pubmed.ncbi.nlm.nih.gov/16640504/ DOI: 10.1042/BA20060044
ERBB2 and KRAS alterations mediate response to EGFR inhibitors in early stage gallbladder cancer Research Papers in Peer Reviewed Journals International Journal of Cancer (Int J Cancer) 0020-7136 144 2020 https://pubmed.ncbi.nlm.nih.gov/30304546/ DOI: 10.1002/ijc.31916
Cytomorphology of spindle cell/sclerosing rhabdomyosarcoma, including MYOD1 (LI22R) mutation result Research Papers in Peer Reviewed Journals Diagnostic Cytopathology 8755-1039 50 2023 https://pubmed.ncbi.nlm.nih.gov/35929754/ DOI: 10.1002/dc.25032
Role of miR-944/MMP10/AXL- axis in lymph node metastasis in tongue cancer Research Papers in Peer Reviewed Journals Communications Biology 2399-3642 6 2023 https://pubmed.ncbi.nlm.nih.gov/36650344/ DOI: 10.1038/s42003-023-04437-6
Recurrent UBE3C-LRP5 translocations in head and neck cancer with therapeutic implications Research Papers in Peer Reviewed Journals npj Precision Oncology 2515-1354 8 2023 https://www.nature.com/articles/s41698-024-00555-4 doi.org/10.1038/s41698-024-00555-4
A Rare Case of A Low-Grade Inflammatory Leiomyosarcoma/Histiocyte-Rich Rhabdomyoblastic Tumor in the Neck of An Adolescent Male Research Papers in Peer Reviewed Journals Turkish Journal of Pathology (Turk Patoloji Derg) 1018-5615 39 2023 https://pubmed.ncbi.nlm.nih.gov/35642345/ DOI: 10.5146/tjpath.2022.01577
Identifying cancer driver genes from functional genomics screens Research Papers in Peer Reviewed Journals Swiss Medical Weekly 1424-7860 150 2021 https://pubmed.ncbi.nlm.nih.gov/32083704/ DOI: 10.4414/smw.2020.20195
Molecular characterization of lung squamous cell carcinoma tumors reveals therapeutically relevant alterations Research Papers in Peer Reviewed Journals Oncotarget 1949-2553 12 2022 https://pubmed.ncbi.nlm.nih.gov/33796225/ DOI: 10.18632/oncotarget.27905
RET Alterations Differentiate Molecular Profile of Medullary Thyroid Cancer Research Papers in Peer Reviewed Journals JCO Precis Oncol 2473-4284 8 2023 https://pubmed.ncbi.nlm.nih.gov/38754058/ doi: 10.1200/PO.23.00622
TMC-SNPdb: an Indian germline variant database derived from whole exome sequences Research Papers in Peer Reviewed Journals The Journal of Biological Databases and Curation 1758-0463 5 https://pubmed.ncbi.nlm.nih.gov/27402678/ DOI: 10.1093/database/baw104
Mitocurcumin utilizes oxidative stress to upregulate JNK/p38 signaling and overcomes Cytarabine resistance in acute myeloid leukemia Research Papers in Peer Reviewed Journals Cellular signalling 0898-6568 114 2023 https://pubmed.ncbi.nlm.nih.gov/38048856/ https://doi.org/10.1016/j.cellsig.2023.111004
Development and characterization of a patient‑derived orthotopic xenograft of therapy‑resistant breast cancer Research Papers in Peer Reviewed Journals Oncology Reports 1021-335X 49 2023 https://pubmed.ncbi.nlm.nih.gov/36999625/ DOI: 10.3892/or.2023.8536
Singleton mutations in large-scale cancer genome studies: uncovering the tail of cancer genome Research Papers in Peer Reviewed Journals NAR Cancer 2603-9299 6 2023 https://academic.oup.com/narcancer/article/6/1/zcae010/7626437 https://doi.org/10.1093/narcan/zcae010
Association of Cutibacterium acnes with human thyroid cancer Research Papers in Peer Reviewed Journals Frontiers in Endocrinology (Lausanne) 1664-2392. 14 2023 https://pubmed.ncbi.nlm.nih.gov/38027096/ https://doi.org/10.3389/fendo.2023.1152514
Novel covalent CDK7 inhibitor potently induces apoptosis in acute myeloid leukemia and synergizes with Venetoclax Research Papers in Peer Reviewed Journals Journal of Experimental & Clinical Cancer Research 1756-9966 42 2023 https://pubmed.ncbi.nlm.nih.gov/37507802/ DOI: 10.1186/s13046-023-02750-w
Metabolic rewiring in drug resistant cells exhibit higher OXPHOS and fatty acids as preferred major source to cellular energetics Research Papers in Peer Reviewed Journals Biochimica et Biophysica Acta (BBA) - Bioenergetics 0005-2728 1861 2021 https://pubmed.ncbi.nlm.nih.gov/32858000/ DOI: 10.1016/j.bbabio.2020.148300
Relationship between the persistence of mer operon sequences in Escherichia coli and their resistance to mercury Research Papers in Peer Reviewed Journals Current Microbiology 0343-8651 44 2003 https://pubmed.ncbi.nlm.nih.gov/11821925/ DOI: 10.1007/s00284-001-0085-6
Up-regulation of the kinase gene SGK1 by progesterone activates the AP-1-NDRG1 axis in both PR-positive and -negative breast cancer cells Research Papers in Peer Reviewed Journals Journal of Biological Chemistry (JBC) 0021-9258 293 2019 https://pubmed.ncbi.nlm.nih.gov/30337371/ DOI: 10.1074/jbc.RA118.002894
Weekly osimertinib dosing prevents EGFR mutant tumor cells destined to home mouse lungs Research Papers in Peer Reviewed Journals Translational Oncology 1936-5233 14 2022 https://pubmed.ncbi.nlm.nih.gov/33993094/ doi: 10.1016/j.tranon.2021.101111
TMC-SNPdb 2.0: an ethnic-specific database of Indian germline variants Research Papers in Peer Reviewed Journals The Journal of Biological Databases and Curation 1758-0463 2022 2023 https://pubmed.ncbi.nlm.nih.gov/35551364/ DOI: 10.1093/database/baac029
High-throughput oncogene mutation profiling in human cancer Research Papers in Peer Reviewed Journals Nature Genetics 1061-4036 39 2008 https://pubmed.ncbi.nlm.nih.gov/17293865/ DOI: 10.1038/ng1975
Circulating nucleic acids damage DNA of healthy cells by integrating into their genomes Research Papers in Peer Reviewed Journals Journal of Biosciences (J Biosci) 0250-5991 40 2016 https://pubmed.ncbi.nlm.nih.gov/25740145/ DOI: 10.1007/s12038-015-9508-6
Unique spectral markers discern recurrent Glioblastoma cells from heterogeneous parent population Research Papers in Peer Reviewed Journals Scientific Reports 2045-2322 6 2017 https://pubmed.ncbi.nlm.nih.gov/27221528/ DOI: 10.1038/srep26538
EGFR mutations in Indian lung cancer patients: clinical correlation and outcome to EGFR targeted therapy Research Papers in Peer Reviewed Journals PLoS ONE 1932-6203 8 https://pubmed.ncbi.nlm.nih.gov/23620765/ DOI: 10.1371/journal.pone.0061561
MYOD1 (L122R) mutations are associated with spindle cell and sclerosing rhabdomyosarcomas with aggressive clinical outcomes Research Papers in Peer Reviewed Journals Modern Pathology 0893-3952 29 2017 https://pubmed.ncbi.nlm.nih.gov/27562493/ DOI: 10.1038/modpathol.2016.144
Analysis of solid tumor mutation profiles in liquid biopsy Research Papers in Peer Reviewed Journals Cancer Medicine 2045-7634 7 2019 https://pubmed.ncbi.nlm.nih.gov/30264478/ DOI: 10.1002/cam4.1791
Impact of intra-tumoral IL17A and IL32 gene expression on T-cell responses and lymph node status in breast cancer patients Research Papers in Peer Reviewed Journals Journal of Cancer Research and Clinical Oncology 0171-5216 143 2018 https://pubmed.ncbi.nlm.nih.gov/28470472/ DOI: 10.1007/s00432-017-2431-5
CRE: a cost effective and rapid approach for PCR-mediated concatenation of KRAS and EGFR exons: Rapid way to detect EGFR and KRAS mutations Research Papers in Peer Reviewed Journals F1000Research 2046-1402 4 2016 https://pubmed.ncbi.nlm.nih.gov/27127615/ DOI: 10.12688/f1000research.6663.2
Inhibitor-sensitive FGFR1 amplification in human non-small cell lung cancer Research Papers in Peer Reviewed Journals PLoS One 1932-6203 6 2012 https://pubmed.ncbi.nlm.nih.gov/21666749/ DOI: 10.1371/journal.pone.0020351
Merkel cell polyomavirus is implicated in a subset of Merkel cell carcinomas, in the Indian subcontinent Research Papers in Peer Reviewed Journals Microbial Pathogenesis 0882-4010 137 2020 https://pubmed.ncbi.nlm.nih.gov/31600537/ DOI: 10.1016/j.micpath.2019.103778
Raman spectroscopy-based detection of RNA viruses in saliva: A preliminary report Research Papers in Peer Reviewed Journals Journal of Biophotonics 1864-063X 13 2021 https://pubmed.ncbi.nlm.nih.gov/32609429/ doi: 10.1002/jbio.202000189
Glioblastoma-derived epidermal growth factor receptor carboxyl-terminal deletion mutants are transforming and are sensitive to EGFR-directed therapies Research Papers in Peer Reviewed Journals Cancer Research 0008-5472. 71 2012 https://pubmed.ncbi.nlm.nih.gov/22001862/ DOI: 10.1158/0008-5472.CAN-11-0821
Impact of Molecular Tumor Board on the Clinical Management of Patients With Cancer Research Papers in Peer Reviewed Journals JCO Global Oncology 2687-8941 8 2023 https://pubmed.ncbi.nlm.nih.gov/35802838/ DOI: 10.1200/GO.22.00030
A structure-guided approach to creating covalent FGFR inhibitors Research Papers in Peer Reviewed Journals Chemistry & Biology 1074-5521. 17 2011 https://pubmed.ncbi.nlm.nih.gov/20338520/ DOI: 10.1016/j.chembiol.2010.02.007
Actionable Activating Oncogenic ERBB2/HER2 Transmembrane and Juxtamembrane Domain Mutations Research Papers in Peer Reviewed Journals Cancer Cell 1535-6108 34 2019 https://pubmed.ncbi.nlm.nih.gov/30449325/ DOI: 10.1016/j.ccell.2018.09.010
SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas Research Papers in Peer Reviewed Journals Nature Genetics 1061-4036 41 2010 https://pubmed.ncbi.nlm.nih.gov/19801978/ DOI: 10.1038/ng.465
Fusobacterium nucleatum is associated with inflammation and poor survival in early-stage HPV-negative tongue cancer Research Papers in Peer Reviewed Journals NAR Cancer 2603-9299 4 2023 https://pubmed.ncbi.nlm.nih.gov/35252868/ DOI: 10.1093/narcan/zcac006
Gallbladder cancer: a journey of a thousand steps Research Papers in Peer Reviewed Journals Future Oncology 1479-6694 14 2019 https://pubmed.ncbi.nlm.nih.gov/29722272/ DOI: 10.2217/fon-2017-0576
Integrated genomic profiling of endometrial carcinoma associates aggressive tumors with indicators of PI3 kinase activation Research Papers in Peer Reviewed Journals Proceedings of the National Academy of Sciences of the United States of America (PNAS) 0027-8424. 106 2010 https://pubmed.ncbi.nlm.nih.gov/19261849/ DOI: 10.1073/pnas.0806514106
The Global Cancer Genomics Consortium: interfacing genomics and cancer medicine Research Papers in Peer Reviewed Journals Cancer Research 0008-5472. 72 2013 https://pubmed.ncbi.nlm.nih.gov/22628426/ DOI: 10.1158/0008-5472.CAN-12-1054
Epidermal growth factor receptor exon 20 mutation in lung cancer: types, incidence, clinical features and impact on treatment Research Papers in Peer Reviewed Journals OncoTargets and Therapy 1178-6930. 10 2018 https://pubmed.ncbi.nlm.nih.gov/28652772/ DOI: 10.2147/OTT.S133245
Frequency of EGFR mutations in 907 lung adenocarcioma patients of Indian ethnicity Research Papers in Peer Reviewed Journals PLoS ONE 1932-6203 8 2015 https://pubmed.ncbi.nlm.nih.gov/24124538/ DOI: 10.1371/journal.pone.0076164
Single nucleotide polymorphism array analysis of cancer Review Articles Current Opinion in Oncology 1040-8746 19 2008 https://pubmed.ncbi.nlm.nih.gov/16857817/ DOI: 10.1097/CCO.0b013e328011a8c1
Coexistence of KRAS mutation with mutant but not wild-type EGFR predicts response to tyrosine-kinase inhibitors in human lung cancer Research Papers in Peer Reviewed Journals British Journal of Cancer 0007-0920 111 2015 https://pubmed.ncbi.nlm.nih.gov/25117816/ DOI: 10.1038/bjc.2014.401
Epidermal growth factor receptor mutation subtypes and geographical distribution among Indian non-small cell lung cancer patients Research Papers in Peer Reviewed Journals Indian Journal of Cancer 0019-509X. 50 2014 https://pubmed.ncbi.nlm.nih.gov/23979200/ DOI: 10.4103/0019-509X.117023
The fight against cancer: Is it worthwhile? Research Papers in Peer Reviewed Journals Indian Journal of Medical and Paediatric Oncology 0971-5851 36 2016 https://pubmed.ncbi.nlm.nih.gov/26157283/ DOI: 10.4103/0971-5851.158833
Progesterone suppresses the invasion and migration of breast cancer cells irrespective of their progesterone receptor status - a short report Research Papers in Peer Reviewed Journals Cellular Oncology (Dordrecht) 2211-3436 40 2018 https://pubmed.ncbi.nlm.nih.gov/28653288/ DOI: 10.1007/s13402-017-0330-z
Enhanced proteasomal activity is essential for long term survival and recurrence of innately radiation resistant residual glioblastoma cells Research Papers in Peer Reviewed Journals Oncotarget 1949-2553 9 2019 https://pubmed.ncbi.nlm.nih.gov/29963228/ DOI: 10.18632/oncotarget.25351
The cancer-associated, gain-of-function TP53 variant P152Lp53 activates multiple signaling pathways implicated in tumorigenesis Research Papers in Peer Reviewed Journals Journal of Biological Chemistry 0021-9258 294 2020 https://pubmed.ncbi.nlm.nih.gov/31366730/ DOI: 10.1074/jbc.RA118.007265
To improve outcomes of gallbladder cancer we need to better understand it! Research Papers in Peer Reviewed Journals Hepatobiliary Surgery and Nutrition 2304-3881. 5 2017 https://pubmed.ncbi.nlm.nih.gov/27500397/ DOI: 10.21037/hbsn.2016.05.06
Gefitinib Versus Gefitinib Plus Pemetrexed and Carboplatin Chemotherapy in EGFR-Mutated Lung Cancer Research Papers in Peer Reviewed Journals Journal of Clinical Oncology 0732-183X 38 2021 https://pubmed.ncbi.nlm.nih.gov/31411950/ DOI: 10.1200/JCO.19.01154
Pre-operative progesterone benefits operable breast cancer patients by modulating surgical stress Research Papers in Peer Reviewed Journals Breast Cancer Research and Treatmen 0167-6806 170 2019 https://pubmed.ncbi.nlm.nih.gov/29564740/ DOI: 10.1007/s10549-018-4749-3
Validation of liquid biopsy: plasma cell-free DNA testing in clinical management of advanced non-small cell lung cancer Research Papers in Peer Reviewed Journals Lung Cancer (Auckland) 1179-2728. 9 2019 https://pubmed.ncbi.nlm.nih.gov/29379323/ DOI: 10.2147/LCTT.S147841
Inhibition of SETMAR-H3K36me2-NHEJ repair axis in residual disease cells prevents glioblastoma recurrence Research Papers in Peer Reviewed Journals Neuro-Oncology 1522-8517 22 2021 https://pubmed.ncbi.nlm.nih.gov/32458986/ DOI: 10.1093/neuonc/noaa128
Lung cancer with dual EGFR and ALK driver alterations at baseline: a retrospective observational cohort study Research Papers in Peer Reviewed Journals Acta Oncologica 0284-186X 61 2023 https://pubmed.ncbi.nlm.nih.gov/35972844/ DOI: 10.1080/0284186X.2022.2109426
Drug-sensitive FGFR2 mutations in endometrial carcinoma Research Papers in Peer Reviewed Journals Proceedings of the National Academy of Sciences of the United States of America (PNAS) 0027-8424 105 2009 https://pubmed.ncbi.nlm.nih.gov/18552176/ DOI: 10.1073/pnas.0803379105
CytoPred: 7-gene pair metric for AML cytogenetic risk prediction Research Papers in Peer Reviewed Journals Briefings in Bioinformatics 1467-5463 21 2021 https://pubmed.ncbi.nlm.nih.gov/30380003/ DOI: 10.1093/bib/bby100
miR-129-2 mediates down-regulation of progesterone receptor in response to progesterone in breast cancer cells Research Papers in Peer Reviewed Journals Cancer Biology & Therapy 1538-4047 18 2018 https://pubmed.ncbi.nlm.nih.gov/28876975/ DOI: 10.1080/15384047.2017.1373216
A one-step, one-tube real-time RT-PCR based assay with an automated analysis for detection of SARS-CoV-2 Research Papers in Peer Reviewed Journals Heliyon 2405-8440 6 2021 https://pubmed.ncbi.nlm.nih.gov/32665985/ DOI: 10.1016/j.heliyon.2020.e04405
Chromatin protein PC4 is downregulated in breast cancer to promote disease progression: Implications of miR-29a Research Papers in Peer Reviewed Journals Oncotarget 1949-2553 10 2020 https://pubmed.ncbi.nlm.nih.gov/31839879/ DOI: 10.18632/oncotarget.27325
A study on p53 gene alterations in esophageal squamous cell carcinoma and their correlation to common dietary risk factors among population of the Kashmir valley Research Papers in Peer Reviewed Journals World Journal of Gastroenterology 1007-9327. 12 2007 https://pubmed.ncbi.nlm.nih.gov/16810754/ DOI: 10.3748/wjg.v12.i25.4033
Non-typhoidal Salmonella DNA traces in gallbladder cancer Research Papers in Peer Reviewed Journals Infectious Agents and Cancer 1750-9378 11 2017 https://pubmed.ncbi.nlm.nih.gov/26941832/ DOI: 10.1186/s13027-016-0057-x
Mouse models of lung cancer Review Articles Clinical Cancer Research 1078-0432 12 2007 https://pubmed.ncbi.nlm.nih.gov/16857817/ DOI: 10.1158/1078-0432.CCR-06-0414
Notch pathway activation is essential for maintenance of stem-like cells in early tongue cancer Research Papers in Peer Reviewed Journals Oncotarget 1949-2553 7 2017 https://pubmed.ncbi.nlm.nih.gov/27391340/ DOI: 10.18632/oncotarget.10419
Somatic mutations affect key pathways in lung adenocarcinoma Research Papers in Peer Reviewed Journals Nature 0028-0836 455 2009 https://pubmed.ncbi.nlm.nih.gov/18948947/ DOI: 10.1038/nature07423
Somatic mutations are present in all members of the AKT family in endometrial carcinoma Research Papers in Peer Reviewed Journals British Journal of Cancer 0007-0920 101 2010 https://pubmed.ncbi.nlm.nih.gov/19738612/ DOI: 10.1038/sj.bjc.6605301
Genomic characterization of tobacco/nut chewing HPV-negative early stage tongue tumors identify MMP10 asa candidate to predict metastases Research Papers in Peer Reviewed Journals Oral Oncology 1368-8375. 73 2018 https://pubmed.ncbi.nlm.nih.gov/28939077/ DOI: 10.1016/j.oraloncology.2017.08.003
Surgical Tumor Resection Deregulates Hallmarks of Cancer in Resected Tissue and the Surrounding Microenvironment Research Papers in Peer Reviewed Journals Mol Cancer Res 1541-7786 22 2024 https://pubmed.ncbi.nlm.nih.gov/38394149/ https://doi.org/10.1158/1541-7786.MCR-23-0265
EGF signal propagation during C. elegans vulval development mediated by ROM-1 rhomboid Research Papers in Peer Reviewed Journals PLoS Biology 1544-9173. 2 2005 https://pubmed.ncbi.nlm.nih.gov/15455032/ DOI: 10.1371/journal.pbio.0020334
Amplification of chromosomal segment 4q12 in non-small cell lung cancer Research Papers in Peer Reviewed Journals Cancer Biology & Therapy 1538-4047 8 2010 https://pubmed.ncbi.nlm.nih.gov/19755855/ DOI: 10.4161/cbt.8.21.9764
A genetic model for gallbladder carcinogenesis and its dissemination Review Articles Annals of Oncology 0923-7534 25 2015 https://pubmed.ncbi.nlm.nih.gov/24705974/ DOI: 10.1093/annonc/mdu006
NGS-based approach to determine the presence of HPV and their sites of integration in human cancer genome Research Papers in Peer Reviewed Journals British Journal of Cancer 0007-0920 112 2016 https://pubmed.ncbi.nlm.nih.gov/25973533/ DOI: 10.1038/bjc.2015.121
IPD 2.0: To derive insights from an evolving SARS-CoV-2 genome Research Papers in Peer Reviewed Journals BMC Bioinformatics 1471-2105 22 2022 https://pubmed.ncbi.nlm.nih.gov/33985433/  doi: 10.1186/s12859-021-04172-x
Molecular cloning and genetic analysis of functional merB gene from indian isolates of Escherichia coli Research Papers in Peer Reviewed Journals Current Microbiology 0343-8651. 51 2006 https://pubmed.ncbi.nlm.nih.gov/16211434/ DOI: 10.1007/s00284-005-0013-2
An integrated approach to determine the abundance, mutation rate and phylogeny of the SARS-CoV-2 genome Research Papers in Peer Reviewed Journals Briefings in Bioinformatics 1467-5463 22 2022 https://pubmed.ncbi.nlm.nih.gov/33479725/ DOI: 10.1093/bib/bbaa437
Cytomorphology of spindle cell/sclerosing rhabdomyosarcoma, including MYOD1 (LI22R) mutation result Research Papers in Peer Reviewed Journals Diagnostic Cytopathology 8755-1039 50 2023 https://pubmed.ncbi.nlm.nih.gov/35929754/ DOI: 10.1002/dc.25032
Somatic mutations affect key pathways in lung adenocarcinoma Research Papers in Peer Reviewed Journals Nature 0028-0836 455 2009 https://pubmed.ncbi.nlm.nih.gov/18948947/ DOI: 10.1038/nature07423
Frequency of EGFR mutations in 907 lung adenocarcioma patients of Indian ethnicity Research Papers in Peer Reviewed Journals PLoS ONE 1932-6203 8 2015 https://pubmed.ncbi.nlm.nih.gov/24124538/ DOI: 10.1371/journal.pone.0076164
Gallbladder cancer: a journey of a thousand steps Research Papers in Peer Reviewed Journals Future Oncology 1479-6694 14 2019 https://pubmed.ncbi.nlm.nih.gov/29722272/ DOI: 10.2217/fon-2017-0576
A study on p53 gene alterations in esophageal squamous cell carcinoma and their correlation to common dietary risk factors among population of the Kashmir valley Research Papers in Peer Reviewed Journals World Journal of Gastroenterology 1007-9327. 12 2007 https://pubmed.ncbi.nlm.nih.gov/16810754/ DOI: 10.3748/wjg.v12.i25.4033
CytoPred: 7-gene pair metric for AML cytogenetic risk prediction Research Papers in Peer Reviewed Journals Briefings in Bioinformatics 1467-5463 21 2021 https://pubmed.ncbi.nlm.nih.gov/30380003/ DOI: 10.1093/bib/bby100
Somatic mutations are present in all members of the AKT family in endometrial carcinoma Research Papers in Peer Reviewed Journals British Journal of Cancer 0007-0920 101 2010 https://pubmed.ncbi.nlm.nih.gov/19738612/ DOI: 10.1038/sj.bjc.6605301
Drug-sensitive FGFR2 mutations in endometrial carcinoma Research Papers in Peer Reviewed Journals Proceedings of the National Academy of Sciences of the United States of America (PNAS) 0027-8424 105 2009 https://pubmed.ncbi.nlm.nih.gov/18552176/ DOI: 10.1073/pnas.0803379105
Cell-free chromatin from dying cancer cells integrate into genomes of bystander healthy cells to induce DNA damage and inflammation Research Papers in Peer Reviewed Journals Cell Death Discovery 2058-7716. 3 2018 https://pubmed.ncbi.nlm.nih.gov/28580170/ DOI: 10.1038/cddiscovery.2017.15
CRE: a cost effective and rapid approach for PCR-mediated concatenation of KRAS and EGFR exons: Rapid way to detect EGFR and KRAS mutations Research Papers in Peer Reviewed Journals F1000Research 2046-1402 4 2016 https://pubmed.ncbi.nlm.nih.gov/27127615/ DOI: 10.12688/f1000research.6663.2
Progesterone modulates the DSCAM-AS1/miR-130a/ESR1 axis to suppress cell invasion and migration in breast cancer Research Papers in Peer Reviewed Journals Breast Cancer Research 1465-5411 24 2023 https://pubmed.ncbi.nlm.nih.gov/36578092/ DOI: 10.1186/s13058-022-01597-x
Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer Research Papers in Peer Reviewed Journals Cancer Discovery 2159-8274. 1 2012 https://pubmed.ncbi.nlm.nih.gov/22328973/ DOI: 10.1158/2159-8274.CD-11-0005
Relationship between the persistence of mer operon sequences in Escherichia coli and their resistance to mercury Research Papers in Peer Reviewed Journals Current Microbiology 0343-8651 44 2003 https://pubmed.ncbi.nlm.nih.gov/11821925/ DOI: 10.1007/s00284-001-0085-6
A one-step, one-tube real-time RT-PCR based assay with an automated analysis for detection of SARS-CoV-2 Research Papers in Peer Reviewed Journals Heliyon 2405-8440 6 2021 https://pubmed.ncbi.nlm.nih.gov/32665985/ DOI: 10.1016/j.heliyon.2020.e04405
Fusobacterium nucleatum is associated with inflammation and poor survival in early-stage HPV-negative tongue cancer Research Papers in Peer Reviewed Journals NAR Cancer 2603-9299 4 2023 https://pubmed.ncbi.nlm.nih.gov/35252868/ DOI: 10.1093/narcan/zcac006
Merkel cell polyomavirus is implicated in a subset of Merkel cell carcinomas, in the Indian subcontinent Research Papers in Peer Reviewed Journals Microbial Pathogenesis 0882-4010 137 2020 https://pubmed.ncbi.nlm.nih.gov/31600537/ DOI: 10.1016/j.micpath.2019.103778
Genomic characterization of tobacco/nut chewing HPV-negative early stage tongue tumors identify MMP10 asa candidate to predict metastases Research Papers in Peer Reviewed Journals Oral Oncology 1368-8375. 73 2018 https://pubmed.ncbi.nlm.nih.gov/28939077/ DOI: 10.1016/j.oraloncology.2017.08.003
Circulating nucleic acids damage DNA of healthy cells by integrating into their genomes Research Papers in Peer Reviewed Journals Journal of Biosciences (J Biosci) 0250-5991 40 2016 https://pubmed.ncbi.nlm.nih.gov/25740145/ DOI: 10.1007/s12038-015-9508-6
Analysis of solid tumor mutation profiles in liquid biopsy Research Papers in Peer Reviewed Journals Cancer Medicine 2045-7634 7 2019 https://pubmed.ncbi.nlm.nih.gov/30264478/ DOI: 10.1002/cam4.1791
Osimertinib for lung cancer cells harboring low-frequency EGFR T790M mutation Research Papers in Peer Reviewed Journals Translational Oncology 1936-5233 22 2023 https://pubmed.ncbi.nlm.nih.gov/35653897/ DOI: 10.1016/j.tranon.2022.101461
Cell-free chromatin from dying cancer cells integrate into genomes of bystander healthy cells to induce DNA damage and inflammation Research Papers in Peer Reviewed Journals Cell Death Discovery 2058-7716. 3 2018 https://pubmed.ncbi.nlm.nih.gov/28580170/ DOI: 10.1038/cddiscovery.2017.15
Inhibition of SETMAR-H3K36me2-NHEJ repair axis in residual disease cells prevents glioblastoma recurrence Research Papers in Peer Reviewed Journals Neuro-Oncology 1522-8517 22 2021 https://pubmed.ncbi.nlm.nih.gov/32458986/ DOI: 10.1093/neuonc/noaa128
Up-regulation of the kinase gene SGK1 by progesterone activates the AP-1-NDRG1 axis in both PR-positive and -negative breast cancer cells Research Papers in Peer Reviewed Journals Journal of Biological Chemistry (JBC) 0021-9258 293 2019 https://pubmed.ncbi.nlm.nih.gov/30337371/ DOI: 10.1074/jbc.RA118.002894
ERBB2 and KRAS alterations mediate response to EGFR inhibitors in early stage gallbladder cancer Research Papers in Peer Reviewed Journals International Journal of Cancer (Int J Cancer) 0020-7136 144 2020 https://pubmed.ncbi.nlm.nih.gov/30304546/ DOI: 10.1002/ijc.31916
Notch pathway activation is essential for maintenance of stem-like cells in early tongue cancer Research Papers in Peer Reviewed Journals Oncotarget 1949-2553 7 2017 https://pubmed.ncbi.nlm.nih.gov/27391340/ DOI: 10.18632/oncotarget.10419
Enhanced proteasomal activity is essential for long term survival and recurrence of innately radiation resistant residual glioblastoma cells Research Papers in Peer Reviewed Journals Oncotarget 1949-2553 9 2019 https://pubmed.ncbi.nlm.nih.gov/29963228/ DOI: 10.18632/oncotarget.25351
Chromatin protein PC4 is downregulated in breast cancer to promote disease progression: Implications of miR-29a Research Papers in Peer Reviewed Journals Oncotarget 1949-2553 10 2020 https://pubmed.ncbi.nlm.nih.gov/31839879/ DOI: 10.18632/oncotarget.27325
Epidermal growth factor receptor mutation subtypes and geographical distribution among Indian non-small cell lung cancer patients Research Papers in Peer Reviewed Journals Indian Journal of Cancer 0019-509X. 50 2014 https://pubmed.ncbi.nlm.nih.gov/23979200/ DOI: 10.4103/0019-509X.117023
miR-129-2 mediates down-regulation of progesterone receptor in response to progesterone in breast cancer cells Research Papers in Peer Reviewed Journals Cancer Biology & Therapy 1538-4047 18 2018 https://pubmed.ncbi.nlm.nih.gov/28876975/ DOI: 10.1080/15384047.2017.1373216
The fight against cancer: Is it worthwhile? Research Papers in Peer Reviewed Journals Indian Journal of Medical and Paediatric Oncology 0971-5851 36 2016 https://pubmed.ncbi.nlm.nih.gov/26157283/ DOI: 10.4103/0971-5851.158833
Impact of Molecular Tumor Board on the Clinical Management of Patients With Cancer Research Papers in Peer Reviewed Journals JCO Global Oncology 2687-8941 8 2023 https://pubmed.ncbi.nlm.nih.gov/35802838/ DOI: 10.1200/GO.22.00030
TMC-SNPdb 2.0: an ethnic-specific database of Indian germline variants Research Papers in Peer Reviewed Journals The Journal of Biological Databases and Curation 1758-0463 2022 2023 https://pubmed.ncbi.nlm.nih.gov/35551364/ DOI: 10.1093/database/baac029
IPD 2.0: To derive insights from an evolving SARS-CoV-2 genome Research Papers in Peer Reviewed Journals BMC Bioinformatics 1471-2105 22 2022 https://pubmed.ncbi.nlm.nih.gov/33985433/  doi: 10.1186/s12859-021-04172-x
Progesterone suppresses the invasion and migration of breast cancer cells irrespective of their progesterone receptor status - a short report Research Papers in Peer Reviewed Journals Cellular Oncology (Dordrecht) 2211-3436 40 2018 https://pubmed.ncbi.nlm.nih.gov/28653288/ DOI: 10.1007/s13402-017-0330-z
Actionable Activating Oncogenic ERBB2/HER2 Transmembrane and Juxtamembrane Domain Mutations Research Papers in Peer Reviewed Journals Cancer Cell 1535-6108 34 2019 https://pubmed.ncbi.nlm.nih.gov/30449325/ DOI: 10.1016/j.ccell.2018.09.010
Integrated genomic profiling of endometrial carcinoma associates aggressive tumors with indicators of PI3 kinase activation Research Papers in Peer Reviewed Journals Proceedings of the National Academy of Sciences of the United States of America (PNAS) 0027-8424. 106 2010 https://pubmed.ncbi.nlm.nih.gov/19261849/ DOI: 10.1073/pnas.0806514106
NGS-based approach to determine the presence of HPV and their sites of integration in human cancer genome Research Papers in Peer Reviewed Journals British Journal of Cancer 0007-0920 112 2016 https://pubmed.ncbi.nlm.nih.gov/25973533/ DOI: 10.1038/bjc.2015.121
SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas Research Papers in Peer Reviewed Journals Nature Genetics 1061-4036 41 2010 https://pubmed.ncbi.nlm.nih.gov/19801978/ DOI: 10.1038/ng.465
Mouse models of lung cancer Review Articles Clinical Cancer Research 1078-0432 12 2007 https://pubmed.ncbi.nlm.nih.gov/16857817/ DOI: 10.1158/1078-0432.CCR-06-0414
High-throughput oncogene mutation profiling in human cancer Research Papers in Peer Reviewed Journals Nature Genetics 1061-4036 39 2008 https://pubmed.ncbi.nlm.nih.gov/17293865/ DOI: 10.1038/ng1975
Integrated genomics approach to identify biologically relevant alterations in fewer samples Research Papers in Peer Reviewed Journals BMC Genomics 1471-2164. 16 2016 https://pubmed.ncbi.nlm.nih.gov/26572163/ DOI: 10.1186/s12864-015-2138-4
Gefitinib Versus Gefitinib Plus Pemetrexed and Carboplatin Chemotherapy in EGFR-Mutated Lung Cancer Research Papers in Peer Reviewed Journals Journal of Clinical Oncology 0732-183X 38 2021 https://pubmed.ncbi.nlm.nih.gov/31411950/ DOI: 10.1200/JCO.19.01154
An integrated approach to determine the abundance, mutation rate and phylogeny of the SARS-CoV-2 genome Research Papers in Peer Reviewed Journals Briefings in Bioinformatics 1467-5463 22 2022 https://pubmed.ncbi.nlm.nih.gov/33479725/ DOI: 10.1093/bib/bbaa437
Non-typhoidal Salmonella DNA traces in gallbladder cancer Research Papers in Peer Reviewed Journals Infectious Agents and Cancer 1750-9378 11 2017 https://pubmed.ncbi.nlm.nih.gov/26941832/ DOI: 10.1186/s13027-016-0057-x
EGFR mutations in Indian lung cancer patients: clinical correlation and outcome to EGFR targeted therapy Research Papers in Peer Reviewed Journals PLoS ONE 1932-6203 8 https://pubmed.ncbi.nlm.nih.gov/23620765/ DOI: 10.1371/journal.pone.0061561
A preliminary investigation demonstrating the effect of quercetin on the expression of genes related to cell-cycle arrest, apoptosis and xenobiotic metabolism in human CO115 colon-adenocarcinoma cells using DNA microarray Research Papers in Peer Reviewed Journals Biotechnology and Applied Biochemistry 0885-4513 45 2007 https://pubmed.ncbi.nlm.nih.gov/16640504/ DOI: 10.1042/BA20060044
Lung cancer with dual EGFR and ALK driver alterations at baseline: a retrospective observational cohort study Research Papers in Peer Reviewed Journals Acta Oncologica 0284-186X 61 2023 https://pubmed.ncbi.nlm.nih.gov/35972844/ DOI: 10.1080/0284186X.2022.2109426
Identifying cancer driver genes from functional genomics screens Research Papers in Peer Reviewed Journals Swiss Medical Weekly 1424-7860 150 2021 https://pubmed.ncbi.nlm.nih.gov/32083704/ DOI: 10.4414/smw.2020.20195
A structure-guided approach to creating covalent FGFR inhibitors Research Papers in Peer Reviewed Journals Chemistry & Biology 1074-5521. 17 2011 https://pubmed.ncbi.nlm.nih.gov/20338520/ DOI: 10.1016/j.chembiol.2010.02.007
Coexistence of KRAS mutation with mutant but not wild-type EGFR predicts response to tyrosine-kinase inhibitors in human lung cancer Research Papers in Peer Reviewed Journals British Journal of Cancer 0007-0920 111 2015 https://pubmed.ncbi.nlm.nih.gov/25117816/ DOI: 10.1038/bjc.2014.401
Metabolic rewiring in drug resistant cells exhibit higher OXPHOS and fatty acids as preferred major source to cellular energetics Research Papers in Peer Reviewed Journals Biochimica et Biophysica Acta (BBA) - Bioenergetics 0005-2728 1861 2021 https://pubmed.ncbi.nlm.nih.gov/32858000/ DOI: 10.1016/j.bbabio.2020.148300
A genetic model for gallbladder carcinogenesis and its dissemination Review Articles Annals of Oncology 0923-7534 25 2015 https://pubmed.ncbi.nlm.nih.gov/24705974/ DOI: 10.1093/annonc/mdu006
Raman spectroscopy-based detection of RNA viruses in saliva: A preliminary report Research Papers in Peer Reviewed Journals Journal of Biophotonics 1864-063X 13 2021 https://pubmed.ncbi.nlm.nih.gov/32609429/ doi: 10.1002/jbio.202000189
Glioblastoma-derived epidermal growth factor receptor carboxyl-terminal deletion mutants are transforming and are sensitive to EGFR-directed therapies Research Papers in Peer Reviewed Journals Cancer Research 0008-5472. 71 2012 https://pubmed.ncbi.nlm.nih.gov/22001862/ DOI: 10.1158/0008-5472.CAN-11-0821
Single nucleotide polymorphism array analysis of cancer Review Articles Current Opinion in Oncology 1040-8746 19 2008 https://pubmed.ncbi.nlm.nih.gov/16857817/ DOI: 10.1097/CCO.0b013e328011a8c1
To improve outcomes of gallbladder cancer we need to better understand it! Research Papers in Peer Reviewed Journals Hepatobiliary Surgery and Nutrition 2304-3881. 5 2017 https://pubmed.ncbi.nlm.nih.gov/27500397/ DOI: 10.21037/hbsn.2016.05.06
Amplification of chromosomal segment 4q12 in non-small cell lung cancer Research Papers in Peer Reviewed Journals Cancer Biology & Therapy 1538-4047 8 2010 https://pubmed.ncbi.nlm.nih.gov/19755855/ DOI: 10.4161/cbt.8.21.9764
Inhibitor-sensitive FGFR1 amplification in human non-small cell lung cancer Research Papers in Peer Reviewed Journals PLoS One 1932-6203 6 2012 https://pubmed.ncbi.nlm.nih.gov/21666749/ DOI: 10.1371/journal.pone.0020351
The cancer-associated, gain-of-function TP53 variant P152Lp53 activates multiple signaling pathways implicated in tumorigenesis Research Papers in Peer Reviewed Journals Journal of Biological Chemistry 0021-9258 294 2020 https://pubmed.ncbi.nlm.nih.gov/31366730/ DOI: 10.1074/jbc.RA118.007265
Weekly osimertinib dosing prevents EGFR mutant tumor cells destined to home mouse lungs Research Papers in Peer Reviewed Journals Translational Oncology 1936-5233 14 2022 https://pubmed.ncbi.nlm.nih.gov/33993094/ doi: 10.1016/j.tranon.2021.101111
Molecular cloning and genetic analysis of functional merB gene from indian isolates of Escherichia coli Research Papers in Peer Reviewed Journals Current Microbiology 0343-8651. 51 2006 https://pubmed.ncbi.nlm.nih.gov/16211434/ DOI: 10.1007/s00284-005-0013-2
MYOD1 (L122R) mutations are associated with spindle cell and sclerosing rhabdomyosarcomas with aggressive clinical outcomes Research Papers in Peer Reviewed Journals Modern Pathology 0893-3952 29 2017 https://pubmed.ncbi.nlm.nih.gov/27562493/ DOI: 10.1038/modpathol.2016.144
Molecular characterization of lung squamous cell carcinoma tumors reveals therapeutically relevant alterations Research Papers in Peer Reviewed Journals Oncotarget 1949-2553 12 2022 https://pubmed.ncbi.nlm.nih.gov/33796225/ DOI: 10.18632/oncotarget.27905
Pre-operative progesterone benefits operable breast cancer patients by modulating surgical stress Research Papers in Peer Reviewed Journals Breast Cancer Research and Treatmen 0167-6806 170 2019 https://pubmed.ncbi.nlm.nih.gov/29564740/ DOI: 10.1007/s10549-018-4749-3
Unique spectral markers discern recurrent Glioblastoma cells from heterogeneous parent population Research Papers in Peer Reviewed Journals Scientific Reports 2045-2322 6 2017 https://pubmed.ncbi.nlm.nih.gov/27221528/ DOI: 10.1038/srep26538
Validation of liquid biopsy: plasma cell-free DNA testing in clinical management of advanced non-small cell lung cancer Research Papers in Peer Reviewed Journals Lung Cancer (Auckland) 1179-2728. 9 2019 https://pubmed.ncbi.nlm.nih.gov/29379323/ DOI: 10.2147/LCTT.S147841
The Global Cancer Genomics Consortium: interfacing genomics and cancer medicine Research Papers in Peer Reviewed Journals Cancer Research 0008-5472. 72 2013 https://pubmed.ncbi.nlm.nih.gov/22628426/ DOI: 10.1158/0008-5472.CAN-12-1054
EGF signal propagation during C. elegans vulval development mediated by ROM-1 rhomboid Research Papers in Peer Reviewed Journals PLoS Biology 1544-9173. 2 2005 https://pubmed.ncbi.nlm.nih.gov/15455032/ DOI: 10.1371/journal.pbio.0020334
Drug-sensitive FGFR3 mutations in lung adenocarcinoma Research Papers in Peer Reviewed Journals Annals of Oncology 0923-7534. 28 2018 https://pubmed.ncbi.nlm.nih.gov/27998968/ DOI: 10.1093/annonc/mdw636
Impact of intra-tumoral IL17A and IL32 gene expression on T-cell responses and lymph node status in breast cancer patients Research Papers in Peer Reviewed Journals Journal of Cancer Research and Clinical Oncology 0171-5216 143 2018 https://pubmed.ncbi.nlm.nih.gov/28470472/ DOI: 10.1007/s00432-017-2431-5
TMC-SNPdb: an Indian germline variant database derived from whole exome sequences Research Papers in Peer Reviewed Journals The Journal of Biological Databases and Curation 1758-0463 5 https://pubmed.ncbi.nlm.nih.gov/27402678/ DOI: 10.1093/database/baw104
Epidermal growth factor receptor exon 20 mutation in lung cancer: types, incidence, clinical features and impact on treatment Research Papers in Peer Reviewed Journals OncoTargets and Therapy 1178-6930. 10 2018 https://pubmed.ncbi.nlm.nih.gov/28652772/ DOI: 10.2147/OTT.S133245
Research Projects
Project Title Project Type Year Of Sanction Outcome/Output Duration
AI-based prediction of metastasis in tongue cancer Minor 2025 The project is approved, awaiting release order-- currently under financial concurrence at the funding agency. Ongoing since 01-07-2024 (10 months, 16 days)
To establish Shodhvik oncology liquid biopsy hotspot assay platform Major 2024-04-01 NA Ongoing since 01-04-2024 (1 years, 1 months, 16 days)
Multi-Omics analysis to decipher mechanisms of hormone resistance and development of novel assays and therapeutic targets in endocrine receptor positive breast cancer Major 2017-04-01 NA 01-04-2017 To 31-03-2022 (4 years, 11 months, 30 days)
Deciphering the role of classical and non-classical pathways regulated by glucocorticoid and androgen receptors in triple negative breast cancer Minor 2023-09-23 NA Ongoing since 23-09-2023 (1 years, 7 months, 24 days)
Defining the cancer genome of head and neck squamous cell carcinoma (HNSCC) with snp arrays and next generation sequencing technology Major 2012-04-01 NA 01-04-2012 To 31-03-2018 (5 years, 11 months, 30 days)
Whole genome sequencing for identification of oncogenic mutations in cervical adenocarcinoma Major 2013-04-01 NA 01-04-2013 To 31-03-2017 (3 years, 11 months, 30 days)
Profiling the incidence of novel alteration discovered in human lung cancer Minor 2011-04-01 NA 01-04-2011 To 30-03-2012 (11 months, 29 days)
Profiling the incidence of novel alteration discovered in human lung cancer Minor 2012-04-01 NA 01-04-2012 To 31-03-2013 (11 months, 30 days)
Epidemiological study to evaluate the prevalence of epidermal growth factor receptor(EGFR mutation status in non-small cell lung cancer(NSCLC) in india. Minor 2012-04-01 NA 01-04-2012 To 31-03-2015 (2 years, 11 months, 30 days)
Characterizing the Mechanistic Insights and Clinical Relevance of Fusobacterium in Tongue Cancer Minor 2023-07-21 NA Ongoing since 21-07-2023 (1 years, 9 months, 26 days)
Genome-wide RNAi screen with human pooled tyrosine kinase shRNA libraries in head and neck squamous cell carcinoma (HNSCC) cell lines Major 2012-04-01 NA 01-04-2012 To 31-03-2017 (4 years, 11 months, 30 days)
Progestonomics of human breast cancer: a translational approach Major 2012-04-01 NA 01-04-2012 To 20-03-2031 (18 years, 11 months, 19 days)
Understanding the mechanistics of resistance to tyrosine kinase inhibitors in non-small cell lung cancer patients. Minor 2018-04-01 NA 01-04-2018 To 31-03-2021 (2 years, 11 months, 30 days)
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