Title Dr. First Name Vijay Last Name Prajapati
Designation Associate Professor
Department Department of Biochemistry SDC
Email vkp@south.du.ac.in
Webpage
Phone.no 07597271362
Employement Info
Employee Type Nature Of Employment
Teaching Permanent
Educational
Degree/Certification Institution Year
Ph.D. - A Study on Chemotherapeutic aspects of visceral leishmaniasis: novel approaches Banaras Hindu University 2012
PG Banaras Hindu University 2006
UG Banaras Hindu University 2004
Fellow Academies
Academy Name Name Of Award Year Of Award
Indian Academy of Sciences, Benguluru Associate 2016
National Academy of Agricultural Sciences Associate 2017
The National Academy of Sciences, India Member 2014
Research Guidance
PhD scholars under Supervision Awarded PhD Submitted
3 2
Research Publications
Article Name Publication Type Journal Name ISSN No Volume Year URL DOI
Exploring malaria parasite surface proteins to devise highly immunogenic multi-epitope subunit vaccine for Plasmodium falciparum Research Papers in UGC listed Journals Journal of Genetic Engineering and Biotechnology doi: 10.1016/j.jgeb.2024.100377 10.1016/j.jgeb.2024.100377

Design of inhibitor peptide sequences based on the interfacial knowledge of the protein G-IgG crystallographic complex and their binding studies with IgG Research Papers in Peer Reviewed Journals European Biophysics Journal 10.1007/s00249-024-01704-0

Peptide-ligand conjugate based immunotherapeutic approach for targeted dismissal of non-structural protein 1 of dengue virus: A novel therapeutic solution for mild and severe dengue infections Research Papers in Peer Reviewed Journals International Journal of Biological Macromolecules 10.1016/j.ijbiomac.2024.129562

Lanosterol elevates cytoprotective response through induced-proteasomal degradation of aberrant proteins Research Papers in Peer Reviewed Journals Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 10.1016/j.bbamcr.2023.119631

Prediction of an immunogenic peptide ensemble and multi-subunit vaccine for Visceral leishmaniasis using bioinformatics approaches Research Papers in Peer Reviewed Journals Heliyon 10.1016/j.heliyon.2023.e22121

Multifaceted mutational immunotherapeutic approach to design therapeutic mAbs to combat monkeypox disease via integrated screening algorithms and antibody engineering Research Papers in Peer Reviewed Journals Molecular Systems Design & Engineering 10.1039/D3ME00059A

Cloning, expression and in vitro validation of chimeric multi epitope vaccine candidate against visceral leishmaniasis infection Research Papers in Peer Reviewed Journals Life Sciences 10.1016/j.lfs.2023.121689

Role of Telomeres and Telomerase in Parkinson's Disease-A New Theranostics? Review Articles Advanced Biology 10.1002/adbi.202300097

Molecular Chaperones’ Potential against Defective Proteostasis of Amyotrophic Lateral Sclerosis. Review Articles Cells 10.3390/cells12091302

A review of chromium (Cr) epigenetic toxicity and health hazards Review Articles Science of the Total Environment 10.1016/j.scitotenv.2023.163483

Plant Products for Antiviral Therapeutics Review Articles Frontiers in Pharmacology doi: 10.3389/fphar.2022.1039183.

Complex Inclusion Bodies and Defective Proteome Hubs in Neurodegenerative Disease: New Clues, New Challenges Review Articles Neuroscientist DOI: 10.1177/1073858421989582

Autophagy based cellular physiological strategies target oncogenic progression Review Articles Journal of Cellular Physiology DOI: 10.1002/jcp.30567

Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021 Research Papers in Peer Reviewed Journals The Lancet DOI: 10.1016/S0140-6736(24)00476-8

Multi-pathogen based chimeric vaccine to fight against COVID-19 and concomitant co-infections Research Papers in Peer Reviewed Journals Biotechnology Letters
Translational vaccinomics and structural filtration algorithm to device multiepitope vaccine for catastrophic monkeypox virus Research Papers in Peer Reviewed Journals Computers in Biology and Medicine DOI: 10.1016/j.compbiomed.2022.106497

Identification of multi-targeting natural antiviral peptides to impede SARS-CoV-2 infection Research Papers in Peer Reviewed Journals Structural Chemistry doi: 10.1007/s11224-022-02113-9.

Nanobody-Peptide-Conjugate (NPC) for passive immunotherapy against SARS-CoV-2 Variants of Concern (VOC): A Prospective Pan-Coronavirus Therapeutics Research Papers in Peer Reviewed Journals Molecular Diversity doi: 10.1007/s11030-022-10570-x.

Rational designing of peptide-ligand conjugates-based immunotherapy for the treatment of complicated malaria Research Papers in Peer Reviewed Journals Life Sciences doi: 10.1016/j.lfs.2022.121121.

Anti-IL-10 antibody humanization by SDR grafting with enhanced affinity to neutralize the adverse response of interleukin-10 Research Papers in Peer Reviewed Journals International Journal of Peptide Research and Therapeutics https://doi.org/10.1007/s10989-022-10456-4

Exploring actinomycetes natural products to identify potential multi-target inhibitors against Leishmania donovani Research Papers in Peer Reviewed Journals 3 Biotech doi: 10.1007/s13205-022-03304-1.

MiRNA-SARS-CoV-2 Dialogue and Prospective Anti-COVID-19 Therapies Review Articles Life Sciences doi: 10.1016/j.lfs.2022.120761

High throughput virtual screening of small-molecule inhibitors targeting immune cell checkpoints to discover new immunotherapeutics for human diseases Research Papers in Peer Reviewed Journals Molecular Diversity doi: 10.1007/s11030-022-10452-2.

Febrifugine dihydrochloride as a new oral chemotherapeutic agent against visceral leishmaniasis infection Research Papers in Peer Reviewed Journals Experimental Parasitology doi: 10.1016/j.exppara.2022.108250.

Designing of a bispecific antibody against SARS-CoV-2 spike glycoprotein targeting human entry receptors DPP4 and ACE2 Research Papers in Peer Reviewed Journals Human Immunology doi: 10.1016/j.humimm.2022.01.004.

A comprehensive approach to discover Toxin-Antitoxin systems from human pathogen Helicobacter pylori: A poison and its antidote encapsulated in the genome Research Papers in Peer Reviewed Journals Life Sciences doi: 10.1016/j.lfs.2021.120149.

Pharmacophore based virtual screening, molecular docking, molecular dynamics and MM-GBSA approach for identification of prospective SARS-CoV-2 inhibitor from natural product databases Research Papers in Peer Reviewed Journals Journal of Biomolecular Structure and Dynamics https://doi.org/10.1080/07391102.2020.1824814

Chemical system biology approach to identify multi-targeting FDA inhibitors for treating COVID-19 and associated health complications Research Papers in Peer Reviewed Journals Journal of Biomolecular Structure and Dynamics doi: 10.1080/07391102.2021.1931451

Engineering a multi epitope vaccine against SARS-CoV-2 by exploiting its non-structural and structural proteins Research Papers in Peer Reviewed Journals Journal of Biomolecular Structure and Dynamics doi: 10.1080/07391102.2021.1924265

Cytotoxic T-lymphocyte elicited vaccine against SARS-CoV-2 employing immunoinformatics framework Research Papers in Peer Reviewed Journals Scientific Reports doi: 10.1038/s41598-021-86986-6

Immunoglobulin interface redesigning to enhance lebrikizumab mediated immunomodulation of IL-13 hyper-response Research Papers in Peer Reviewed Journals Journal of Biomolecular Structure and Dynamics DOI: 10.1080/07391102.2020.1773316

Publications other than journal articles
Title of Publication Type of Publication Publisher Role in Publication ISBN Number Year URL Level
System Vaccinology: The History The Translational Challenges and The Future Text/Reference/Subject Books/Other Academic Press Elsevier Editor 10 : 0323859410 International
MicroRNA in Human Infectious Diseases Text/Reference/Subject Books/Other Academic Press Elsevier Editor 9780323996617 International
Advances in Protein Chemistry and Structural Biology (Volume 139) - Translational Bioinformatics Text/Reference/Subject Books/Other Academic Press Elsevier Editor 0443193487 International
Advances in Protein Chemistry and Structural Biology (Volume 140) - Immunology for Engineers Text/Reference/Subject Books/Other Academic Press Elsevier Editor 0443193509 International
Decoding macrophage immunometabolism in human viral infection Chapters in Books Academic Press Elsevier Author 0443193509 International
Exploring structural engineering approach to formulate and characterize next-generation adjuvants Chapters in Books Academic Press Elsevier Author 0443193509 International
Unleashing the power of antibodies: Engineering for tomorrow’s therapy Chapters in Books Academic Press Elsevier Author 0443193509 International
From genome to clinic: The power of translational bioinformatics in improving human health Chapters in Books Academic Press Elsevier Author 0443193487 International
Bioinformatics Approaches in Studying the Fungal Endophyte-Derived Bioactive Compounds with Pharmacological Relevance Chapters in Books Springer Nature Author 978-3-031-49112-2 International
Paradigms in miRNA biogenesis pathways Chapters in Books Academic Press Elsevier Author 978-0-323-99661-7 International
Application of functional proteomics in understanding RNA virus-mediated infection Chapters in Books Academic Press Elsevier Author 978-0-443-19342-2 International
Research Projects
Title of the Project Project Type Year Of Sanction Output Start Date End Date
Quantification and expression of anti-apoptotic and pro-apoptotic proteins of Leishmania parasites for developing novel therapeutics Major 2024 Project started in April 2024 2024-04-25 2028-04-24
Inhibiting glycosomal membrane biogenesis as a potential leishmaniasis treatment Major 2024 Project started in April 2024 2024-04-15 2028-04-14
Faculty Research Programme Grant-IoE 2023 2023-08-31 2024-02-14
Development of natural product derived febrifugine analogues as a novel therapeutics against Visceral Leishmaniasis Major 2016 2016-11-25 2019-03-31
Antileishmanial activity of silver nanoparticles attached to amphotericin B. 2015 2015-10-20 2016-12-31
Molecular and Structural Characterization of Mitochondrial DNA Primase in Leishmania donovani Major 2016 2016-10-24 2019-03-31
Honour And Awards
Name of the Award Name of the Awarding Body Award Category Level Date of Award
Ranbaxy Science Scholar Ranbaxy Science Foundation Research National 2012-02-06
Shakuntla Amir Chand Prize Indian Council of Medical Research Academic National 2014-06-16
INSA Medal for Young Scientist Indian National Science Academy Research National 2015-12-31
ASM-IUSSTF Indo-US Research Professorship American Society for Microbiology (ASM) and Indo-US Science and Technology Forum (IUSSTF) Research International 2016-06-06
Young Scientist Award The Biotech Research Society, India (BRSI) Research National 2016-10-10
Young Scientist Award National Academy of Agricultural Sciences, New Delhi Research National 2017-10-24
Young Scientist Award Indian Society of Chemists & Biologists Research National 2018-06-18
Young Scientist Award Association of Microbiology of India Research National 2018-10-24
Chancellor’s Award for Best Faculty Central University of Rajasthan Academic University 2018-11-02
First Prize in the contest of Young Scientist at conference “Perspective technologies in Vaccination & Immunotehrapy” Russian Academy of Sciences Research International 2018-10-22
Prof. Umakant Sinha Memorial Award Indian Science Congress Association Research National 2019-01-04
Malaviya Memorial Award (Young Faculty) The Biotech Research Society, India (BRSI) Academic National 2022-12-07
Visiting Scientist Fellowship LabEx CeMEB, University of Montpellier Research International 2024-06-10
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