Title Prof. First Name SHRIKANT Last Name KUKRETI
Designation Senior Professor
Department Department of Chemistry
Email skukreti@chemistry.du.ac.in
Webpage
Phone.no 9811953563
Employement Info
Employee Type Nature Of Employment
Teaching Permanent
Educational Qualifications
Degree/Certification Name Institution Year of Completion
Ph.D. - Ph.D. University of Roorkee (IITR) 1989
PG Garhwal University (HNBGU) 1984
UG Garhwal University (HNBGU) 1981
Fellowship Details
Name Of Fellowship Awarding Body Fellowship Level
POST DOCTORAL FELLOWSHIP CNRS, Paris, France International
POST DOCTORAL FELLOWSHIP Foundation Pour La Recherche Medicale”, Paris International
Marie Curie fellowship Commission of European Community” (CEC) DST, Govt. of India International
Teaching & Research Associateship Center for Biotechnology, Jawaharlal Nehru University, New Delhi National
Research Associateship (DST Project) Center for Biotechnology, Jawaharlal Nehru University, New Delhi National
Senior Research Fellowship DST, Govt. of India National
Junior Research Fellowship DST, Govt. of India National
Development of E-content
Name of The Module Platform/Organization Date of Launching
33 Electrophoresis and Isotopes in Biology Other 19-12-2013
34 Introduction to Molecular asymmetry (chirality, enantiomerism, optical activity etc.) Other 19-12-2013
M5; Nucleotides and Polynucleotides Other 19-12-2013
M35- Calixarene, ionophores, micelles, synthetic enzymes or synzymes Other 19-12-2013
Teaching Experience (Within Institution)
Designation Duration
Post Doctoral Fellow 01-09-1994 To 02-09-1997 (3 years, 1 days)
Lecturer 27-01-1998 To 01-08-2001 (3 years, 6 months, 5 days)
Visiting Fellow 02-10-1998 To 02-01-1999 (3 months)
Reader 09-09-2001 To 08-09-2004 (2 years, 11 months, 30 days)
Visiting Fellow 06-06-2004 To 02-10-2004 (3 months, 26 days)
Associate Professor 08-10-2004 To 09-09-2009 (4 years, 11 months, 1 days)
Professor 09-10-2009 To 09-09-2019 (9 years, 11 months)
Senior Professor 09-10-2019 To 14-09-2022 (2 years, 11 months, 5 days)
Research Supervision Overview
PhD Scholars Supervised PhD Degrees Awarded Theses Submitted
6 24 0
M.Phil Scholars Supervised M.Phil Degrees Awarded M.Phil Theses Submitted
0 6 0
Research Publications
Title of Article Type of Publication Name of Journal ISSN Journal Volume Year Link to Article DOI (Digital Object Identifier)
Advance nanotherapeutic approach for systemic co-delivery of mitoxantrone loaded chitosan coated PLGA nanoparticles to improve the chemotherapy against human non-small cell lung cancer Research Papers in Peer Reviewed Journals Journal of Drug Delivery Science and Technology 1773-2247 84 https://www.sciencedirect.com/science/article/pii/S1773224723003751?via%3Dihub https://doi.org/10.1016/j.jddst.2023.104523
Lipid mediated brain disorders: A perspective Research Papers in Peer Reviewed Journals Prostaglandins and Other Lipid Mediators 1098-8823 167 https://pubmed.ncbi.nlm.nih.gov/37086954/ doi: 10.1016/j.prostaglandins.2023.106737
G-quadruplex formation at human DAT1 gene promoter: Effect of cytosine methylation Research Papers in Peer Reviewed Journals Biochemistry and Biophysics Reports 2405-5808 34 https://www.sciencedirect.com/science/article/pii/S2405580823000456?via%3Dihub https://doi.org/10.1016/j.bbrep.2023.101464
Nanomaterials and DNA multistranded structures: a treasure hunt for targeting specific biomedical applications Research Papers in Peer Reviewed Journals Journal of Biomolecular Structure and Dynamics 0739-1102 https://pubmed.ncbi.nlm.nih.gov/36546729/ https://doi.org/10.1080/07391102.2022.2159878
Alkali cation-mediated topology displayed by an exonic G-rich sequence of TRPA1 gene Research Papers in Peer Reviewed Journals Journal of Biomolecular Structure and Dynamics 0739-1102 https://pubmed.ncbi.nlm.nih.gov/36458452/ https://doi.org/10.1080/07391102.2022.2150686
Valproic acid-induced upregulation of multidrug efflux transporter ABCG2/BCRP via PPARα-dependent mechanism in human brain endothelial cells Research Papers in Peer Reviewed Journals Molecular Pharmacology 0026-895X 103 doi: 10.1124/molpharm.122.000568.
Non-canonical DNA structures: Diversity and disease association Research Papers in Peer Reviewed Journals Frontiers in Genetics 1664-8021 https://doi.org/10.3389/fgene.2022.959258
A novel G·G·T non-conventional intramolecular triplex formed by the double repeat sequence of Chlamydomonas telomeric DNA Research Papers in Peer Reviewed Journals RSC Advances 2046-2069 12 2022 https://www.rsc.org/journals-books-databases/about-journals/rsc-advances/ doi: 10.1039/d2ra00861k.

Mechanistic Insight in Oxidative Stress Triggered Signaling Pathways and Type 2 Diabetes Research Papers in Peer Reviewed Journals Molecules 1420-3049 27 2022 https://www.mdpi.com/journal/molecules https://doi.org/10.3390/molecules27030950.
Probing multifunctional azure B conjugated gold nanoparticles with serum protein binding properties for trimodal photothermal, photodynamic, and chemo therapy: Biophysical and photophysical investigations. Research Papers in Peer Reviewed Journals Materials Science and Engineering: C 0928-4931 https://www.journals.elsevier.com/materials-science-and-engineering-c DOI:10.1016/j.msec.2022.112678
Porphyrin induced structural destabilization of a parallel DNA G-quadruplex in human MRP1 gene promoter Research Papers in Peer Reviewed Journals Journal of Molecular Recognition 0952-3499 35 https://onlinelibrary.wiley.com/journal/10991352 doi: 10.1002/jmr.2950.

Structural Switching/ polymorphism by sequential base substitution at quasi-palindromic SNP site (G→A) in LCR of Human β-globin Gene cluster Research Papers in Peer Reviewed Journals International Journal of Biological Macromolecule 0141-8130 201 https://www.sciencedirect.com/journal/international-journal-of-biological-macromolecules https://doi.org/10.1016/j.ijbiomac.2021.12.142
Insights into structural modifications of valproic acid and their pharmacological profile Research Papers in Peer Reviewed Journals Molecules 1420-3049 27 https://www.mdpi.com/journal/molecules https://doi.org/10.3390/molecules27010104
Sequence-Specific Recognition of a Coding Segment of Human DACH1 gene via short Pyrimidine/Purine oligonucleotides Research Papers in Peer Reviewed Journals RSC Advances 2046-2069 11 https://www.rsc.org/journals-books-databases/about-journals/rsc-advances/ DOI https://doi.org/10.1039/D1RA06604H

Multidrug efflux transporter ABCG2: Expression and regulation Research Papers in Peer Reviewed Journals Cellular and Molecular Sciences 1420-9071 78 https://www.springer.com/journal/18 https://doi.org/10.1007/s00018-021-03901-y.
Gold nanoclusters: An ultrasmall platform for multifacted applications Research Papers in Peer Reviewed Journals Talanta 0039-9140 234 https://www.sciencedirect.com/journal/talanta doi: 10.1016/j.talanta.2021.122623.
Designing a two-stage colorimetric sensing strategy based on citrate reduced gold nanoparticles: Sequential detection of Sanguinarine (anticancer drug) and visual sensing of DNA Research Papers in Peer Reviewed Journals Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 1386-1425 246 https://www.sciencedirect.com/journal/spectrochimica-acta-part-a-molecular-and-biomolecular-spectroscopy/vol/246/suppl/C https://doi.org/10.1016/j.saa.2020.119039.
Cationic porphyrins as destabilizer of a G-quadruplex located at the promoter of human MYH7 β gene Research Papers in Peer Reviewed Journals Journal of Biomolecular Structure and Dynamics 0739-1102 16 https://www.tandfonline.com/toc/tbsd20/current https://doi.org/10.1080/07391102.2019.1689850
Interaction of a photosensitizer methylene blue with various structural forms (cruciform, bulge duplex and hairpin) of designed DNA sequences Research Papers in Peer Reviewed Journals Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 1386-1425 242 https://www.sciencedirect.com/journal/spectrochimica-acta-part-a-molecular-and-biomolecular-spectroscopy https://doi.org/10.1016/j.saa.2020.118716
Formation of a DNA triple helical structure at BOLF1 gene of human herpesvirus 4 (HH4) genome. Research Papers in Peer Reviewed Journals Journal of Biomolecular Structure & Dynamics 0739-1102 9 https://www.tandfonline.com/toc/tbsd20/current doi.org/10.1080/07391102.2020.1764390.
Protection by Ethyl Pyruvate against Gamma Radiation Induced Damage in Bovine Serum Albumin Research Papers in Peer Reviewed Journals International Journal of Biological Macromolecule 0141-8130 150 https://doi.org/10.1016/j.ijbiomac.2019.10.110
Self-Association of Coralyne: An ordered thermal destacking. Research Papers in Peer Reviewed Journals Results in Chemistry 2211-7156 2 https://www.sciencedirect.com/journal/results-in-chemistry https://doi.org/10.1016/j.rechem.2020.100043
Exploring potential of i-motif DNA formed in the promoter region of GRIN1 gene for nanotechnological applications Research Papers in Peer Reviewed Journals Results in Chemistry 2211-7156 2 https://www.sciencedirect.com/journal/results-in-chemistry https://doi.org/10.1016/j.rechem.2020.100086
Oxidative Stress: Role and Response of Short Guanine Tracts at Genomic Locations Research Papers in Peer Reviewed Journals Int. J. Mol. Sci. 1422-0067 20 https://www.mdpi.com/journal/ijms https://doi.org/10.3390/ijms20174258
The four repeat Giardia lamblia telomere forms tetramolecular G-quadruplex with antiparallel topology Research Papers in Peer Reviewed Journals Journal of Biomolecular Structure & Dynamics 0739-1102 7 https://www.tandfonline.com/toc/tbsd20/current https://doi.org/10.1080/07391102.2019.1623074
Autosomal dominant Polycystic Kidney Disease: A Review Research Papers in Peer Reviewed Journals Journal of Biomedical and Therpeutic Sciences 2394-2274 6 http://pubs.iscience.in/journal/index.php/jbts urn:nbn:sciencein.jbts.2019v6.101
Exploring the potential of environment friendly silver nanoparticles for DNA interaction: Physicochemical Approach Research Papers in Peer Reviewed Journals Journal of Photochemistry and Photobiology, B: Biology 1011-1344 194 https://www.elsevier.com/journals/journal-of-photochemistry-and-photobiology-b-biology/1011-1344/ https://doi.org/10.1016/j.jphotobiol.2019.03.022
Oxidative Stress: A Key Modulator in Neurodegenerative Diseases Research Papers in Peer Reviewed Journals Molecules 1420-3049 24 https://www.mdpi.com/journal/molecules doi:10.3390/molecules24081583

Viral Induced Oxidative and Inflammatory Response in Alzheimer's Disease Pathogenesis with Identification of Potential Drug Candidates: A Systematic Review using Systems Biology Approach Research Papers in Peer Reviewed Journals Curr Neuropharmacol 1875-6190 17 https://benthamscience.com/journals/current-neuropharmacology/author-guidelines/ doi: 10.2174/1570159X16666180419124508
Unusual Stability Exhibited by (AT) X N 12 (AT) Y Motif Associated With High Fetal Hemoglobin Levels Research Papers in Peer Reviewed Journals Journal of Biomolecular Structure & Dynamics 0739-1102 14 https://www.tandfonline.com/toc/tbsd20/current DOI: 10.1080/07391102.2018.
Synthesis of 3,6 Diaryl-1H-Pyrazolo[3,4-b]Pyridines via One-pot Sequential Suzuki-Miyaura Coupling. Research Papers in Peer Reviewed Journals RSC Advances 2046-2069 8 https://www.rsc.org/journals-books-databases/about-journals/rsc-advances/ DOI: 10.1039/C8RA07104G
Homoduplex to i-motif structural switch exhibited by a Cytosine rich strand of MYH 7 heavy chain β gene promoter at physiological pH. Research Papers in Peer Reviewed Journals RSC Advances 2046-2069 8 https://www.rsc.org/journals-books-databases/about-journals/rsc-advances/ DOI https://doi.org/10.1039/C8RA05179H

Prerequisite of a Holistic Blend of Traditional and Modern Approaches of Cancer Management Research Papers in Peer Reviewed Journals Current Cancer Therapy Reviews 1573-3947 15 https://benthamscience.com/journals/current-cancer-therapy-reviews/ DOI: 10.2174/1573394714666180417160750
Emerging trends in Advanced Nanomaterials based electrochemical genosensors Research Papers in Peer Reviewed Journals Current Pharmaceutical Design 1381-6128 https://benthamscience.com/journals/current-pharmaceutical-design/ DOI: 10.2174/1381612824666181109154919

A topological transition from bimolecular quadruplex to G-triplex/tri-G-quadruplex exhibited by truncated double repeats of human telomere. Research Papers in Peer Reviewed Journals European Biophysics Journal 0175-7571 8 https://www.springer.com/journal/249 doi: 10.1007/s00249-018-1312-4.
Exploring the DNA damaging potential of chitosan and citrate-reduced gold nanoparticles: Physicochemical approach. Research Papers in Peer Reviewed Journals International Journal of Biological Macromolecule 0141-8130 115 https://www.elsevier.com/journals/international-journal-of-biological-macromolecules/0141-8130/guide-for-author doi: 10.1016/j.ijbiomac.2018.04.115.
Formation of G-wires, bimolecular and 2 tetramolecular quadruplex: Cation-induced structural 3 polymorphs of G-rich DNA sequence of human SYTX gene Research Papers in Peer Reviewed Journals Biopolymers 1097-0282 109 https://onlinelibrary.wiley.com/journal/10970282 https://doi.org/10.1002/bip.23115
Structural Switch from Hairpin to Duplex/Antiparallel G-Quadruplex at Single- Nucleotide Polymorphism (SNP) Site of Human Apolipoprotein E (APOE) Gene Coding Region Research Papers in Peer Reviewed Journals ACSOmega 2470-1343 3 https://pubs.acs.org/page/acsodf/about.html https://doi.org/10.1021/acsomega.7b01654
Structural polymorphism of a cytosine-rich DNA sequence forming i-motif structure: Exploring pH based biosensors Research Papers in Peer Reviewed Journals International Journal of Biological Macromolecule 0141-8130 111 https://www.sciencedirect.com/science/article/pii/S0141813017348572 https://doi.org/10.1016/j.ijbiomac.2018.01.053
A Triple Stranded G-Quadruplex Formation In The Promoter Region of Human Myosin  (MYH7) Gene Research Papers in Peer Reviewed Journals Journal of Biomolecular Structure & Dynamics 0739-1102 36 https://www.tandfonline.com/toc/tbsd20/current https://doi.org/10.1080/07391102.2017.1374211
Non-Journal Publications
Title of Publication Type of Publication Publisher Role ISBN Year Link to Publication Level
Deciphering Plausible Role of DNA nanostructures in Drug Delivery Chapters in Books Elsevier Co-Author 9780323961172 https://www.elsevier.com/books/fiber-and-textile-engineering-in-drug-delivery-systems/sharma/978-0-323-96117-2. International
Oxidative Stress and Cellular Dysfunction in Neurodegenerative Disease Chapters in Books Springer (Nature) Series Co-Author ISBN-978-1-0716-1711-3 International
Mapping Genome by using Bioinformatics data and tools Chapters in Books Elsevier Co-Author 978-0-12-821748-1 International
Unveiling the molecular basis of DNA-Protein Structure and function: An in-silico View Chapters in Books Elsevier Co-Author 978-0-12-821748-1 International
Computational and Functional Annotation at Genomic Scale: Gene Expression and Analysis Chapters in Books Elsevier Co-Author 978-0-12-821748-1 International
Decoding DNA Structure using NMR Spectroscopy Chapters in Books Bentham Science Co-Author 9781681086422 International
Research Projects
Project Title Project Type Year Of Sanction Outcome/Output Duration
Physicochemical and Biochemical Investigation of Highly Stable Pyrimidine and Purine Motif DNA Triple Helical Structure Major 2001 Publication 7 19-03-2004 To 18-03-2007 (2 years, 11 months, 27 days)
Biophysical and Biochemical Investigation of the Polymorphic DNA sequences present in Regulatory region of the β-Globin gene cluster Major 2004 Publications 01-04-2004 To 31-12-2006 (2 years, 8 months, 30 days)
Multistranded DNA Recognition: Use of Synthetic Ligands Major 2002 Publications 16-08-2002 To 15-08-2005 (2 years, 11 months, 30 days)
Structural Polymorphism of G-Rich sequences Minor 2020 Publication 31-12-2020 To 15-02-2021 (1 months, 15 days)
Recognition of Structurally Polymorphic G-rich motifs at various functional genomic locations Minor 2021 Publication 29-10-2021 To 31-03-2022 (5 months, 2 days)
Structural Characterization and Recognition of Short Guanine Stretches located at Specific Genomic loci by Designed Peptides Minor 2022 Publication 31-08-2022 To 15-02-2023 (5 months, 15 days)
Targeting Structural Motif adopted by G-rich segment located in the coding region of SHC1 oncogene Minor 2023 Publication 31-08-2023 To 15-02-2024 (5 months, 15 days)
Honors and Awards
Name of the Award Awarding Body Award Category Level Award Date
Visiting Fellowship Department of Molecular Biology, Princeton University, Princeton Academic International 01-06-2004
Visiting Fellowship Institut Gustave Roussy, Villejuif, France Academic International 01-10-1998
Talk Poster Presented
Name of the Activity Role Date of Activity
1. Polymorphic Behaviour of A DNA Sequence Present at The Intersection of Human COMT And Mir4761 Gene Poster Presentation 07-01-2019
Structural Polymorphism exhibited by G-rich sequences in Human WT1 gene Poster Presentation 07-01-2019
Eukaryotic Telomeric Sequence Under Methylation Poster Presentation 07-01-2019
Environment-friendly silver nanoparticles: Investigating the interaction with Calf- Thymus DNA and catalytic reduction of dyes Poster Presentation 07-01-2019
Fluorescent sensor based on protein directed gold nanoclusters for the detection of silver ions and anticancer drugs Poster Presentation 07-01-2019
A Physicochemical approach to study and compare the genotoxic potential of chitosan and citrate reduced gold nanoparticles towards calf thymus DNA Poster Presentation 12-01-2018
A Physicochemical approach to study the genotoxic potential of chitosan and citrate reduced gold nanoparticles towards calf thymus DNA: A physicochemical approach Poster Presentation 11-12-2017
An environmentally benign approach to synthesize Silver nanoparticles using Epipremnum aureum leaf extract and its interaction studies with Calf Thymus DNA Poster Presentation 11-12-2017
In Search of G-Quadruplex Ligand Poster Presentation 07-04-2016
Interaction of an electrochemical redox indicator New Methylene Blue with DNA using biophysical techniques Poster Presentation 01-03-2016
To explore the structural difference between the ɛ3 and ɛ4 allele SNP of the human apolipoprotein (APOE) gene Poster Presentation 06-02-2016
Structural polymorphism exhibited by a quasipalindrome present in Human SCAI gene Poster Presentation 06-02-2016
Identification and Characterization of DNA Quadruplex element in the human GRIN1 promoter region Poster Presentation 25-02-2015
NMR of Biological Macromolecules Poster Presentation 23-08-1993
Recognition of G-Quadruplexes Formed at Promoter Location of Human Myosin Heavy Chain Β Gene (MYH7β) By Natural Alkaloids Oral Presentation 07-01-2019
Recognition and destabilization of Parallel G- quadruplex present in Promoter location of Human MYH7 β gene Oral Presentation 12-01-2018
A Novel Parallel Triple Stranded G-Quadruplex Formation In Promoter Region of Human Myosin  (MYH7) Gene Oral Presentation 11-04-2015
National Symposium on Biophysics and Golden Jubilee Meeting of The Indian Biophysical Society Oral Presentation 14-02-2015
Differential Structural of a RNA counterpart of an undecamer quasi-palindromic DNA sequence present in LCR of human -globin gene cluster Oral Presentation 21-01-2013
Structural polymorphism of Nucleic Acids Oral Presentation 24-02-2012
Presence of divalent cation is not mandatory for the formation of intramolecular purine-motif triplex containing human c-jun protooncogene target Oral Presentation 30-01-2011
DBT-Star College Lecture Series Invited Talk 25-10-2018
Keynote Speaker Invited Talk 04-10-2018
Mentor Lecture Invited Talk 17-12-2018
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