Title Prof. First Name SHRIKANT Last Name KUKRETI
Designation Senior Professor
Department Department of Chemistry
Email skukreti@chemistry.du.ac.in
Webpage
Phone.no 9811953563
Employement Info
Employee Type Nature Of Employment
Teaching Permanent
Educational
Degree/Certification Institution Year
Ph.D. - Protein-Nucleic Acid Interaction University of Roorkee (IITR) 1989
PG Garhwal University (HNBGU) 1984
UG Garhwal University (HNBGU) 1981
Fellowship
Fellowship Name Fellowship Body Level
POST DOCTORAL FELLOWSHIP CNRS, Paris, France International
POST DOCTORAL FELLOWSHIP Foundation Pour La Recherche Medicale”, Paris International
Marie Curie fellowship Commission of European Community” (CEC) DST, Govt. of India International
Teaching & Research Associateship Center for Biotechnology, Jawaharlal Nehru University, New Delhi National
Research Associateship (DST Project) Center for Biotechnology, Jawaharlal Nehru University, New Delhi National
Senior Research Fellowship DST, Govt. of India National
Junior Research Fellowship DST, Govt. of India National
Development of E-content
Institute Academic Year Duties Assigned
33 Electrophoresis and Isotopes in Biology Other 3629
34 Introduction to Molecular asymmetry (chirality, enantiomerism, optical activity etc.) Other 3629
M5; Nucleotides and Polynucleotides Other 3629
M35- Calixarene, ionophores, micelles, synthetic enzymes or synzymes Other 3629
Teaching experience inside the Institution
Designation Institution Duration From Duration To
Post Doctoral Fellow MNHN, Paris and Institute Gustave Roussy (CNRS), Villejuif, Paris, France 1994-09-01 1997-09-02
Lecturer University of Delhi 1998-01-27 2001-08-01
Visiting Fellow Institute Gustave Roussy Villejuif, Paris, France 1998-10-02 1999-01-02
Reader University of Delhi 2001-09-09 2004-09-08
Visiting Fellow Princeton University, Princeton, USA 2004-06-06 2004-10-02
Associate Professor University of Delhi 2004-10-08 2009-09-09
Professor University of Delhi 2009-10-09 2019-09-09
Senior Professor University of Delhi 2019-10-09 2022-09-14
Research Guidance
PhD scholars under Supervision Awarded PhD Submitted
8 23 1
M.Phil Scholars – Under Supervision Awarded Degree Submitted
2
Research Publications
Article Name Publication Type Journal Name ISSN No Volume Year URL DOI
A novel G·G·T non-conventional intramolecular triplex formed by the double repeat sequence of Chlamydomonas telomeric DNA Research Papers in Peer Reviewed Journals RSC Advances 2046-2069 12 2022 https://www.rsc.org/journals-books-databases/about-journals/rsc-advances/ doi: 10.1039/d2ra00861k.

Mechanistic Insight in Oxidative Stress Triggered Signaling Pathways and Type 2 Diabetes Research Papers in Peer Reviewed Journals Molecules 1420-3049 27 2022 https://www.mdpi.com/journal/molecules https://doi.org/10.3390/molecules27030950.
Probing multifunctional azure B conjugated gold nanoparticles with serum protein binding properties for trimodal photothermal, photodynamic, and chemo therapy: Biophysical and photophysical investigations. Research Papers in Peer Reviewed Journals Materials Science and Engineering: C 0928-4931 2022 https://www.journals.elsevier.com/materials-science-and-engineering-c DOI:10.1016/j.msec.2022.112678
Porphyrin induced structural destabilization of a parallel DNA G-quadruplex in human MRP1 gene promoter Research Papers in Peer Reviewed Journals Journal of Molecular Recognition 0952-3499 35 2022 https://onlinelibrary.wiley.com/journal/10991352 doi: 10.1002/jmr.2950.

Structural Switching/ polymorphism by sequential base substitution at quasi-palindromic SNP site (G→A) in LCR of Human β-globin Gene cluster Research Papers in Peer Reviewed Journals International Journal of Biological Macromolecule 0141-8130 201 2022 https://www.sciencedirect.com/journal/international-journal-of-biological-macromolecules https://doi.org/10.1016/j.ijbiomac.2021.12.142
Insights into structural modifications of valproic acid and their pharmacological profile Research Papers in Peer Reviewed Journals Molecules 1420-3049 27 2022 https://www.mdpi.com/journal/molecules https://doi.org/10.3390/molecules27010104
Sequence-Specific Recognition of a Coding Segment of Human DACH1 gene via short Pyrimidine/Purine oligonucleotides Research Papers in Peer Reviewed Journals RSC Advances 2046-2069 11 2021 https://www.rsc.org/journals-books-databases/about-journals/rsc-advances/ DOI https://doi.org/10.1039/D1RA06604H

Multidrug efflux transporter ABCG2: Expression and regulation Research Papers in Peer Reviewed Journals Cellular and Molecular Sciences 1420-9071 78 2021 https://www.springer.com/journal/18 https://doi.org/10.1007/s00018-021-03901-y.
Gold nanoclusters: An ultrasmall platform for multifacted applications Research Papers in Peer Reviewed Journals Talanta 0039-9140 234 2021 https://www.sciencedirect.com/journal/talanta doi: 10.1016/j.talanta.2021.122623.
Designing a two-stage colorimetric sensing strategy based on citrate reduced gold nanoparticles: Sequential detection of Sanguinarine (anticancer drug) and visual sensing of DNA Research Papers in Peer Reviewed Journals Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 1386-1425 246 2021 https://www.sciencedirect.com/journal/spectrochimica-acta-part-a-molecular-and-biomolecular-spectroscopy/vol/246/suppl/C https://doi.org/10.1016/j.saa.2020.119039.
Exploring potential of i-motif DNA formed in the promoter region of GRIN1 gene for nanotechnological applications Research Papers in Peer Reviewed Journals Results in Chemistry 2211-7156 2 2020 https://www.sciencedirect.com/journal/results-in-chemistry https://doi.org/10.1016/j.rechem.2020.100086
Interaction of a photosensitizer methylene blue with various structural forms (cruciform, bulge duplex and hairpin) of designed DNA sequences Research Papers in Peer Reviewed Journals Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 1386-1425 242 2020 https://www.sciencedirect.com/journal/spectrochimica-acta-part-a-molecular-and-biomolecular-spectroscopy https://doi.org/10.1016/j.saa.2020.118716
Formation of a DNA triple helical structure at BOLF1 gene of human herpesvirus 4 (HH4) genome. Research Papers in Peer Reviewed Journals Journal of Biomolecular Structure & Dynamics 0739-1102 9 2020 https://www.tandfonline.com/toc/tbsd20/current doi.org/10.1080/07391102.2020.1764390.
Self-Association of Coralyne: An ordered thermal destacking. Research Papers in Peer Reviewed Journals Results in Chemistry 2211-7156 2 2020 https://www.sciencedirect.com/journal/results-in-chemistry https://doi.org/10.1016/j.rechem.2020.100043
Cationic porphyrins as destabilizer of a G-quadruplex located at the promoter of human MYH7 β gene Research Papers in Peer Reviewed Journals Journal of Biomolecular Structure and Dynamics 0739-1102 16 2020 https://www.tandfonline.com/toc/tbsd20/current https://doi.org/10.1080/07391102.2019.1689850
The four repeat Giardia lamblia telomere forms tetramolecular G-quadruplex with antiparallel topology Research Papers in Peer Reviewed Journals Journal of Biomolecular Structure & Dynamics 0739-1102 7 2020 https://www.tandfonline.com/toc/tbsd20/current https://doi.org/10.1080/07391102.2019.1623074
Protection by Ethyl Pyruvate against Gamma Radiation Induced Damage in Bovine Serum Albumin Research Papers in Peer Reviewed Journals International Journal of Biological Macromolecule 0141-8130 150 2020 https://doi.org/10.1016/j.ijbiomac.2019.10.110
Oxidative Stress: Role and Response of Short Guanine Tracts at Genomic Locations Research Papers in Peer Reviewed Journals Int. J. Mol. Sci. 1422-0067 20 2019 https://www.mdpi.com/journal/ijms https://doi.org/10.3390/ijms20174258
Viral Induced Oxidative and Inflammatory Response in Alzheimer's Disease Pathogenesis with Identification of Potential Drug Candidates: A Systematic Review using Systems Biology Approach Research Papers in Peer Reviewed Journals Curr Neuropharmacol 1875-6190 17 2019 https://benthamscience.com/journals/current-neuropharmacology/author-guidelines/ doi: 10.2174/1570159X16666180419124508
Oxidative Stress: A Key Modulator in Neurodegenerative Diseases Research Papers in Peer Reviewed Journals Molecules 1420-3049 24 2019 https://www.mdpi.com/journal/molecules doi:10.3390/molecules24081583

Autosomal dominant Polycystic Kidney Disease: A Review Research Papers in Peer Reviewed Journals Journal of Biomedical and Therpeutic Sciences 2394-2274 6 2019 http://pubs.iscience.in/journal/index.php/jbts urn:nbn:sciencein.jbts.2019v6.101
Exploring the potential of environment friendly silver nanoparticles for DNA interaction: Physicochemical Approach Research Papers in Peer Reviewed Journals Journal of Photochemistry and Photobiology, B: Biology 1011-1344 194 2019 https://www.elsevier.com/journals/journal-of-photochemistry-and-photobiology-b-biology/1011-1344/ https://doi.org/10.1016/j.jphotobiol.2019.03.022
Unusual Stability Exhibited by (AT) X N 12 (AT) Y Motif Associated With High Fetal Hemoglobin Levels Research Papers in Peer Reviewed Journals Journal of Biomolecular Structure & Dynamics 0739-1102 14 2019 https://www.tandfonline.com/toc/tbsd20/current DOI: 10.1080/07391102.2018.
Emerging trends in Advanced Nanomaterials based electrochemical genosensors Research Papers in Peer Reviewed Journals Current Pharmaceutical Design 1381-6128 2018 https://benthamscience.com/journals/current-pharmaceutical-design/ DOI: 10.2174/1381612824666181109154919

Prerequisite of a Holistic Blend of Traditional and Modern Approaches of Cancer Management Research Papers in Peer Reviewed Journals Current Cancer Therapy Reviews 1573-3947 15 2018 https://benthamscience.com/journals/current-cancer-therapy-reviews/ DOI: 10.2174/1573394714666180417160750
Synthesis of 3,6 Diaryl-1H-Pyrazolo[3,4-b]Pyridines via One-pot Sequential Suzuki-Miyaura Coupling. Research Papers in Peer Reviewed Journals RSC Advances 2046-2069 8 2018 https://www.rsc.org/journals-books-databases/about-journals/rsc-advances/ DOI: 10.1039/C8RA07104G
Homoduplex to i-motif structural switch exhibited by a Cytosine rich strand of MYH 7 heavy chain β gene promoter at physiological pH. Research Papers in Peer Reviewed Journals RSC Advances 2046-2069 8 2018 https://www.rsc.org/journals-books-databases/about-journals/rsc-advances/ DOI https://doi.org/10.1039/C8RA05179H

A Triple Stranded G-Quadruplex Formation In The Promoter Region of Human Myosin  (MYH7) Gene Research Papers in Peer Reviewed Journals Journal of Biomolecular Structure & Dynamics 0739-1102 36 2017 https://www.tandfonline.com/toc/tbsd20/current https://doi.org/10.1080/07391102.2017.1374211
A topological transition from bimolecular quadruplex to G-triplex/tri-G-quadruplex exhibited by truncated double repeats of human telomere. Research Papers in Peer Reviewed Journals European Biophysics Journal 0175-7571 8 2018 https://www.springer.com/journal/249 doi: 10.1007/s00249-018-1312-4.
Exploring the DNA damaging potential of chitosan and citrate-reduced gold nanoparticles: Physicochemical approach. Research Papers in Peer Reviewed Journals International Journal of Biological Macromolecule 0141-8130 115 2018 https://www.elsevier.com/journals/international-journal-of-biological-macromolecules/0141-8130/guide-for-author doi: 10.1016/j.ijbiomac.2018.04.115.
Structural Switch from Hairpin to Duplex/Antiparallel G-Quadruplex at Single- Nucleotide Polymorphism (SNP) Site of Human Apolipoprotein E (APOE) Gene Coding Region Research Papers in Peer Reviewed Journals ACSOmega 2470-1343 3 2018 https://pubs.acs.org/page/acsodf/about.html https://doi.org/10.1021/acsomega.7b01654
Formation of G-wires, bimolecular and 2 tetramolecular quadruplex: Cation-induced structural 3 polymorphs of G-rich DNA sequence of human SYTX gene Research Papers in Peer Reviewed Journals Biopolymers 1097-0282 109 2018 https://onlinelibrary.wiley.com/journal/10970282 https://doi.org/10.1002/bip.23115
Structural polymorphism of a cytosine-rich DNA sequence forming i-motif structure: Exploring pH based biosensors Research Papers in Peer Reviewed Journals International Journal of Biological Macromolecule 0141-8130 111 2018 https://www.sciencedirect.com/science/article/pii/S0141813017348572 https://doi.org/10.1016/j.ijbiomac.2018.01.053
Non-canonical DNA structures: Diversity and disease association Research Papers in Peer Reviewed Journals Frontiers in Genetics 1664-8021 2022 https://doi.org/10.3389/fgene.2022.959258
Alkali cation-mediated topology displayed by an exonic G-rich sequence of TRPA1 gene Research Papers in Peer Reviewed Journals Journal of Biomolecular Structure and Dynamics 0739-1102 2022 https://pubmed.ncbi.nlm.nih.gov/36458452/ https://doi.org/10.1080/07391102.2022.2150686
Valproic acid-induced upregulation of multidrug efflux transporter ABCG2/BCRP via PPARα-dependent mechanism in human brain endothelial cells Research Papers in Peer Reviewed Journals Molecular Pharmacology 0026-895X 103 2023 doi: 10.1124/molpharm.122.000568.
Nanomaterials and DNA multistranded structures: a treasure hunt for targeting specific biomedical applications Research Papers in Peer Reviewed Journals Journal of Biomolecular Structure and Dynamics 0739-1102 2022 https://pubmed.ncbi.nlm.nih.gov/36546729/ https://doi.org/10.1080/07391102.2022.2159878
G-quadruplex formation at human DAT1 gene promoter: Effect of cytosine methylation Research Papers in Peer Reviewed Journals Biochemistry and Biophysics Reports 2405-5808 34 2023 https://www.sciencedirect.com/science/article/pii/S2405580823000456?via%3Dihub https://doi.org/10.1016/j.bbrep.2023.101464
Advance nanotherapeutic approach for systemic co-delivery of mitoxantrone loaded chitosan coated PLGA nanoparticles to improve the chemotherapy against human non-small cell lung cancer Research Papers in Peer Reviewed Journals Journal of Drug Delivery Science and Technology 1773-2247 84 2023 https://www.sciencedirect.com/science/article/pii/S1773224723003751?via%3Dihub https://doi.org/10.1016/j.jddst.2023.104523
Lipid mediated brain disorders: A perspective Research Papers in Peer Reviewed Journals Prostaglandins and Other Lipid Mediators 1098-8823 167 2023 https://pubmed.ncbi.nlm.nih.gov/37086954/ doi: 10.1016/j.prostaglandins.2023.106737
Publications other than journal articles
Title of Publication Type of Publication Publisher Role in Publication ISBN Number Year URL Level
Deciphering Plausible Role of DNA nanostructures in Drug Delivery Chapters in Books Elsevier Co-Author 9780323961172 2023 https://www.elsevier.com/books/fiber-and-textile-engineering-in-drug-delivery-systems/sharma/978-0-323-96117-2. International
Oxidative Stress and Cellular Dysfunction in Neurodegenerative Disease Chapters in Books Springer (Nature) Series Co-Author ISBN-978-1-0716-1711-3 2022 International
Mapping Genome by using Bioinformatics data and tools Chapters in Books Elsevier Co-Author 978-0-12-821748-1 2021 International
Unveiling the molecular basis of DNA-Protein Structure and function: An in-silico View Chapters in Books Elsevier Co-Author 978-0-12-821748-1 2021 International
Computational and Functional Annotation at Genomic Scale: Gene Expression and Analysis Chapters in Books Elsevier Co-Author 978-0-12-821748-1 2021 International
Decoding DNA Structure using NMR Spectroscopy Chapters in Books Bentham Science Co-Author 9781681086422 2019 International
Honour And Awards
Name of the Award Name of the Awarding Body Award Category Level Date of Award
Visiting Fellowship Department of Molecular Biology, Princeton University, Princeton Academic International 2004-06-01
Visiting Fellowship Institut Gustave Roussy, Villejuif, France Academic International 1998-10-01
Seminar / Conference Details / Workshops
Title of the Activity Attended As Date
1. Polymorphic Behaviour of A DNA Sequence Present at The Intersection of Human COMT And Mir4761 Gene Poster Presentation 2019-01-07
Structural Polymorphism exhibited by G-rich sequences in Human WT1 gene Poster Presentation 2019-01-07
Eukaryotic Telomeric Sequence Under Methylation Poster Presentation 2019-01-07
Environment-friendly silver nanoparticles: Investigating the interaction with Calf- Thymus DNA and catalytic reduction of dyes Poster Presentation 2019-01-07
Fluorescent sensor based on protein directed gold nanoclusters for the detection of silver ions and anticancer drugs Poster Presentation 2019-01-07
A Physicochemical approach to study and compare the genotoxic potential of chitosan and citrate reduced gold nanoparticles towards calf thymus DNA Poster Presentation 2018-01-12
A Physicochemical approach to study the genotoxic potential of chitosan and citrate reduced gold nanoparticles towards calf thymus DNA: A physicochemical approach Poster Presentation 2017-12-11
An environmentally benign approach to synthesize Silver nanoparticles using Epipremnum aureum leaf extract and its interaction studies with Calf Thymus DNA Poster Presentation 2017-12-11
In Search of G-Quadruplex Ligand Poster Presentation 2016-04-07
Interaction of an electrochemical redox indicator New Methylene Blue with DNA using biophysical techniques Poster Presentation 2016-03-01
To explore the structural difference between the ɛ3 and ɛ4 allele SNP of the human apolipoprotein (APOE) gene Poster Presentation 2016-02-06
Structural polymorphism exhibited by a quasipalindrome present in Human SCAI gene Poster Presentation 2016-02-06
Identification and Characterization of DNA Quadruplex element in the human GRIN1 promoter region Poster Presentation 2015-02-25
NMR of Biological Macromolecules Poster Presentation 1993-08-23
Recognition of G-Quadruplexes Formed at Promoter Location of Human Myosin Heavy Chain Β Gene (MYH7β) By Natural Alkaloids Oral Presentation 2019-01-07
Recognition and destabilization of Parallel G- quadruplex present in Promoter location of Human MYH7 β gene Oral Presentation 2018-01-12
A Novel Parallel Triple Stranded G-Quadruplex Formation In Promoter Region of Human Myosin  (MYH7) Gene Oral Presentation 2015-04-11
National Symposium on Biophysics and Golden Jubilee Meeting of The Indian Biophysical Society Oral Presentation 2015-02-14
Differential Structural of a RNA counterpart of an undecamer quasi-palindromic DNA sequence present in LCR of human -globin gene cluster Oral Presentation 2013-01-21
Structural polymorphism of Nucleic Acids Oral Presentation 2012-02-24
Presence of divalent cation is not mandatory for the formation of intramolecular purine-motif triplex containing human c-jun protooncogene target Oral Presentation 2011-01-30
DBT-Star College Lecture Series Invited Talk 2018-10-25
Keynote Speaker Invited Talk 2018-10-04
Mentor Lecture Invited Talk 2018-12-17
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