Title Dr. First Name V. THILLAI SEKAR Last Name
Designation Associate Professor
Department Department of Microbiology
Email
Webpage
Phone.no 04162654000
Employement Info
Employee Type Nature Of Employment
Teaching Permanent
Educational Qualifications
Degree/Certification Name Institution Year of Completion
Ph.D. - Doctor of Philosophy University of Madras 2007
Research Publications
Title of Article Type of Publication Name of Journal ISSN Journal Volume Year Link to Article DOI (Digital Object Identifier)
Restoration of the Lost Human Beta Defensin-1 Protein in Cancer as a Strategy to Improve the Efficacy of Chemotherapy Research Papers in UGC listed Journals Journal of Medicinal Chemistry 0022-2623 2024 https://pubmed.ncbi.nlm.nih.gov/39137365/ https://doi.org/10.1021/acs.jmedchem.4c01040

Pancreatic beta cells and islets take up thiamin by a regulated carrier-mediated process: studies using mice and human pancreatic preparations Research Papers in UGC listed Journals American Journal of Physiology - Gastrointestinal and Liver Physiology 297(1), G197-206
Mechanism and regulation of folate uptake by pancreatic acinar cells: effect of chronic alcohol consumption Research Papers in UGC listed Journals American Journal of Physiology - Gastrointestinal and Liver Physiology 298(6), G985-93
Thiamin uptake by pancreatic acinar cells: Effect of chronic alcohol feeding/exposure Research Papers in UGC listed Journals American Journal of Physiology - Gastrointestinal and Liver Physiology 301(5), G896-G904
Engineering intracellularly retained Gaussia Luciferase reporters for improved biosensing and molecular imaging applications. Research Papers in UGC listed Journals ACS Chemical Biology 12(9), 2345-2353
Degron Protease Blockade Sensor to Image Epigenetic Histone Protein Methylation in Cells and Living Animals. Research Papers in UGC listed Journals ACS Chemical Biology 10(1), 165-74
A molecular imaging biosensor detects in 
vivo protein folding and misfolding Research Papers in UGC listed Journals Journal of Molecular Medicine 94(7), 799-808
The Impact of Oxidative Stress on Islet Transplantation and Monitoring the Graft Survival by Non-Invasive Imaging Research Papers in UGC listed Journals Current Medicinal Chemistry 20(9), 1127-46
Proteomic Identification of Pterostilbene-Mediated Anticancer Activities in HepG2 Cells Research Papers in UGC listed Journals Chemical Research in Toxicology 27(7), 1243-1252
A protein folding molecular imaging biosensor monitors the effects of drugs that restore mutant p53 structure and its downstream function in glioblast Research Papers in UGC listed Journals Oncotarget 9(30), 21495
Targeted nanoparticle delivery of therapeutic antisense microRNAs presensitizes glioblastoma cells to lower effective doses of temozolomide in vitro a Research Papers in UGC listed Journals Oncotarget 9(30), 21478
Nrf2 activity as a potential biomarker for the pan-epigenetic anticancer agent, RRx-001 Research Papers in UGC listed Journals Oncotarget 6(25), 21547-56
Monitoring the Antioxidant Mediated Chemosensitization and ARE-Signaling in Triple Negative Breast Cancer Therapy. Research Papers in UGC listed Journals PLoS one 10(11), e0141913
Involvement of Enterobacter cloacae in the mortality of the fish, Mugil cephalus Research Papers in UGC listed Journals Letters in Applied Microbiology 46(6), 667-672
Imaging cellular receptors in breast cancers: An overview Research Papers in UGC listed Journals Current Pharmaceutical Biotechnology 12(4), 508-527
Incidence of white muscle disease, a viral like disease associated with mortalities in hatchery-reared postlarvae of the giant freshwater prawn Macrob Research Papers in UGC listed Journals Aquaculture Research 36(3), 311-316
Polychaete worms--a vector for white spot syndrome virus (WSSV) Research Papers in UGC listed Journals Diseases of Aquatic organisms 63, 107-111
Folate Receptor Targeted Polymeric Micellar Nanocarriers for Delivery of Orlistat as a Repurposed Drug against Triple Negative Breast Cancer. Research Papers in UGC listed Journals Molecular Cancer Therapeutics 15(2): 221-31
Polymer nanoparticles mediated codelivery of antimiR-10b and antimiR-21 for achieving triple negative breast cancer therapy Research Papers in UGC listed Journals ACS Nano 9(3), 2290-302
Noninvasive Theranostic Imaging of HSV1-sr39TK-NTR/GCV-CB1954 Dual-Prodrug Therapy in Metastatic Lung Lesions of MDA-MB-231 Triple Negative Breast Can Research Papers in UGC listed Journals Theranostics 4(5), 460
Therapeutic Evaluation of microRNAs by Molecular Imaging Research Papers in UGC listed Journals Theranostics 3(12), 964-85
Gemcitabine and antisense-microRNA co-encapsulated PLGA–PEG polymer nanoparticles for hepatocellular carcinoma therapy. Research Papers in UGC listed Journals ACS Applied Materials & interfaces 8(49), 33412-33422
Therapeutic potential of pterostilbene against pancreatic β-cell apoptosis through Nrf2 mechanism Research Papers in UGC listed Journals British Journal of Pharmacology 171(7), 1747-1757
Molecular Imaging Biosensor Monitors p53 Sumoylation in Cells and Living Mice. Research Papers in UGC listed Journals Analytical Chemistry 88(23), 11420-28
Reporter protein complementation imaging assay to screen and study Nrf2 activators in cells and living animals Research Papers in UGC listed Journals Analytical Chemistry 85(15), 7542-7549
Genetically Encoded Molecular Biosensors to Image Histone Methylation in Living Animals Research Papers in UGC listed Journals Analytical Chemistry 87(2), 892-9
Simultaneous selection of nanobodies for accessible epitopes on immune cells in the tumor microenvironment Research Papers in UGC listed Journals Nature Communications 14, Article No. 7473
Oxidative stress-mediated cytotoxicity and apoptosis induction by TiO 2 nanofibers in HeLa cells Research Papers in UGC listed Journals European Journal Pharmaceutics and Biopharmaceutics 81(2), 324-333
Noninvasive optical imaging of nitroreductase gene-directed enzyme prodrug therapy system in living animals Research Papers in UGC listed Journals Gene Therapy 19(3), 295-302
Dual-therapeutic reporter genes fusion for enhanced cancer gene therapy and imaging Research Papers in UGC listed Journals Gene Therapy 20(5), 529-37
A transgenic mouse model expressing an ERα folding biosensor reveals the effects of Bisphenol A on estrogen receptor signaling. Research Papers in UGC listed Journals Scientific Reports 6, 34788
Formulation of anti-miR-21 and 4-hydroxytamoxyfen co-loaded biodegradable polymer nanoparticles and its anti-proliferative effect on breast cancer cel Research Papers in UGC listed Journals Molecular Pharmaceutics 12(6), 2080-92
Biotin uptake by mouse and human pancreatic beta cells/islets: A regulated, lipopolysaccharides-sensitive carrier-mediated process Research Papers in UGC listed Journals American Journal of Physiology - Gastrointestinal and Liver Physiology 307(3), G365-73
Ultrasound-guided delivery of thymidine kinase–nitroreductase dual therapeutic genes by PEGylated-PLGA/PEI nanoparticles for enhanced triple negativ Research Papers in UGC listed Journals Nanomedicine 13(9), 1051-1066
Non-Journal Publications
Title of Publication Type of Publication Publisher Role ISBN Year Link to Publication Level
Imaging Histone Methylations in Living Animals Chapters in Books Springer Author 1970 National
Theranostic Imaging of Cancer gene Therapy Chapters in Books Springer Author 1970 National
Bioluminescence Imaging of cancer therapy Chapters in Books Academic Press, Elsevier Inc. Author 1970 National
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